Artículo
Measurements of association constants between enantiomers and chiral selectors by capillary gas chromatography. Theoretical and practical considerations
Lebed, Pablo Jorge
; Keunchkarian, Sonia
; Osorio Grisales, Jaiver
; Castells, Cecilia Beatriz Marta




Fecha de publicación:
01/2014
Editorial:
Elsevier Science
Revista:
Journal Of Chromatography - A
ISSN:
0021-9673
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Resumen
The association constants of several volatile enantiomers with octakis(3-O-butanoyl-2,6-di-O-pentyl)-γ-cyclodextrin at temperatures between 50 and 100 °C were measured by gas–liquid chromatography using capillary columns coated with different amounts of chiral selector dissolved in polysiloxane OV-1701 and prepared with a precisely determined phase ratio. Simple expressions were deduced to estimate the apparent distribution constants from accurate hold-up and retention times along with that known phase ratio at each temperature. The enantiomer-chiral selector association constants were then calculated from the linear regression of the apparent constants as a function of the chiral selector concentration. One aim of this study consisted in discussing all the experimental uncertainties inherent in the determination of enantiomer/selector association constants with chiral analytes, and how these fundamental measurements can be performed precisely without resorting to the use of reference solutes.
Archivos asociados
http://dx.doi.org/10.1016/j.chroma.2013.11.007
http://www.sciencedirect.com/science/article/pii/S0021967313017627
http://www.sciencedirect.com/science/article/pii/S0021967313017627

Citación:
Lebed, Pablo Jorge; Keunchkarian, Sonia; Osorio Grisales, Jaiver; Castells, Cecilia Beatriz Marta; Measurements of association constants between enantiomers and chiral selectors by capillary gas chromatography. Theoretical and practical considerations; Elsevier Science; Journal Of Chromatography - A; 1324; 1-2014; 198-206
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Articulos(CIDEPINT) [98]
Articulos de CENTRO DE INV EN TECNOLOGIA DE PINTURAS (I)