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dc.contributor.author
Toneatto, Judith
dc.contributor.author
Charó, Nancy Lorena
dc.contributor.author
Galigniana, Natalia Maricel
dc.contributor.author
Piwien Pilipuk, Graciela
dc.date.available
2020-08-10T18:53:38Z
dc.date.issued
2015-05
dc.identifier.citation
Toneatto, Judith; Charó, Nancy Lorena; Galigniana, Natalia Maricel; Piwien Pilipuk, Graciela; Adipogenesis is Under Surveillance of Hsp90 and the High Molecular Weight Immunophilin FKBP51; Taylor & Francis; Adipocyte; 4; 4; 5-2015; 239--247
dc.identifier.issn
2162-3945
dc.identifier.uri
http://hdl.handle.net/11336/111339
dc.description.abstract
Adipose tissue plays a central role in the control of energy balance as well as in the maintenance of metabolic homeostasis. It was not until recently that the first evidences of the role of heat shock protein (Hsp) 90 and high molecular weight immunophilin FKBP51 have been described in the process of adipocyte differentiation. Recent reports describe their role in the regulation of PPARγ, a key transcription factor in the control of adipogenesis and the maintenance of the adipocyte phenotype. In addition, novel roles have been uncovered for FKBP51 in the organization of the architecture of the nucleus through its participation in the reorganization of the nuclear lamina. Therefore, the aim of this review is to integrate and discuss the recent advances in the field, with special emphasis on the roles of Hsp90 and FKBP51 in the process of adipocyte differentiation.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Taylor & Francis
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
ADIPOGENESIS
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HSP90
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FKBP51
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PPARgamma
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NUCLEAR LAMINA
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Bioquímica y Biología Molecular
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Adipogenesis is Under Surveillance of Hsp90 and the High Molecular Weight Immunophilin FKBP51
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-08-05T16:55:08Z
dc.identifier.eissn
2162-397X
dc.journal.volume
4
dc.journal.number
4
dc.journal.pagination
239--247
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Toneatto, Judith. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.fil
Fil: Charó, Nancy Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.fil
Fil: Galigniana, Natalia Maricel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.fil
Fil: Piwien Pilipuk, Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.journal.title
Adipocyte
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1080/21623945.2015.1049401
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573184/
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info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1080/21623945.2015.1049401