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López, Graciela
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Assali Serruya, Raphael
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Barchuk, Magalí
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Gaitan-Charry, Diego
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Torres-Leal, Francisco Leonardo
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Moreno, Luis Alberto
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Delgado, Carlos Alberto
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Barbosa Carvalho, Heráclito
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De Moraes, Augusto César Ferreira
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Berg, Gabriela
dc.date.available
2020-07-13T15:46:45Z
dc.date.issued
2020-01
dc.identifier.citation
López, Graciela; Assali Serruya, Raphael; Barchuk, Magalí; Gaitan-Charry, Diego; Torres-Leal, Francisco Leonardo; et al.; Sampling and processing blood samples within the South American Youth/Child cARdiovascular and Environmental (SAYCARE) Study; Springer; Scientific Reports; 10; 1; 1-2020; 1-7
dc.identifier.issn
2045-2322
dc.identifier.uri
http://hdl.handle.net/11336/109144
dc.description.abstract
Obesity and overweight in children and adolescents is increasing rapidly worldwide; however, scarce data have been reported from South America countries. With the purpose of assessing hyperlipidemia, insulin resistance and chronic inflammation, the evaluation of blood biomarkers such as glucose, lipoproteins and chronic inflammation proteins is required. In the context of the SAYCARE study, in children and adolescents (3 to 18 years) from seven South American cities, our aim was to assess the impact of pre analytical conditions on different biomarkers evaluated in 474 fresh serum samples, in different country centers. We also evaluated the stability according to time and frozen storage within this study across the concordance of the results obtained from the 49 blood samples measured in three different centers. Significant correlations as well as concordance were observed in TG, Total-C, HDL-C and glucose between Buenos Aires and São Paulo. The samples evaluated in Teresina and São Paulo presented similar results, with exception of total cholesterol. We observed acceptable concordance between Buenos Aires vs São Paulo and Teresina vs São Paulo, suggesting that samples could be processed in each of these centers. This concordance is a consequence of the strict pre analytical conditions previously established in the SAYCARE study.
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application/pdf
dc.language.iso
eng
dc.publisher
Springer
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dc.rights
info:eu-repo/semantics/openAccess
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https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
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BIOMARKERS
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HEALTH CARE
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RISK FACTORS
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Otras Ciencias de la Salud
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Ciencias de la Salud
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CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Sampling and processing blood samples within the South American Youth/Child cARdiovascular and Environmental (SAYCARE) Study
dc.type
info:eu-repo/semantics/article
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info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-07-01T17:09:16Z
dc.identifier.eissn
2045-2322
dc.journal.volume
10
dc.journal.number
1
dc.journal.pagination
1-7
dc.journal.pais
Reino Unido
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dc.description.fil
Fil: López, Graciela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina
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Fil: Assali Serruya, Raphael. Universidade de Sao Paulo; Brasil
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Fil: Barchuk, Magalí. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina
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Fil: Gaitan-Charry, Diego. Universidad de Antioquia; Colombia
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Fil: Torres-Leal, Francisco Leonardo. Universidade Federal Do Piaui.; Brasil
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Fil: Moreno, Luis Alberto. Universidad de Zaragoza; España
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Fil: Delgado, Carlos Alberto. Universidad Nacional Mayor de San Marcos; Perú
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Fil: Barbosa Carvalho, Heráclito. Universidade de Sao Paulo; Brasil
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Fil: De Moraes, Augusto César Ferreira. Universidade de Sao Paulo; Brasil
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Fil: Berg, Gabriela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina
dc.journal.title
Scientific Reports
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.nature.com/articles/s41598-020-57457-1
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1038/s41598-020-57457-1
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