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dc.contributor.author
Carlo, Waldemar A.
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Goudar, Shivaprasad S.
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Jehan, Imtiaz
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Chomba, Elwyn
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Tshefu, Antoinette
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Garces, Ana
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Sailajanandan, Parida
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Althabe, Fernando
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McClure, Elizabeth M.
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Derman, Richard J.
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Goldenberg, Robert L.
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Bose, Carl
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Krebs, Nancy F.
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Panigrahi, Pinaki
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Buekens, Pierre
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Chakraborty, Hrishikesh
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Hartwell, Tyler D.
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Wright, Linda L.
dc.date.available
2020-06-18T15:48:47Z
dc.date.issued
2010-02
dc.identifier.citation
Carlo, Waldemar A.; Goudar, Shivaprasad S.; Jehan, Imtiaz; Chomba, Elwyn; Tshefu, Antoinette; et al.; Newborn-Care Training and Perinatal Mortality in Developing Countries; Massachusetts Medical Society; New England Journal of Medicine; 362; 7; 2-2010; 614-623
dc.identifier.issn
0028-4793
dc.identifier.uri
http://hdl.handle.net/11336/107614
dc.description.abstract
BACKGROUND: Of the 3.7 million neonatal deaths and 3.3 million stillbirths each year, 98% occur in developing countries. An evaluation of community-based interventions designed to reduce the number of these deaths is needed. METHODS: With the use of a train-the-trainer model, local instructors trained birth attendants from rural communities in six countries (Argentina, Democratic Republic of Congo, Guatemala, India, Pakistan, and Zambia) in the World Health Organization Essential Newborn Care course (which focuses on routine neonatal care, resuscitation, thermoregulation, breast-feeding, "kangaroo" [skin-to-skin] care, care of the small baby, and common illnesses) and (except in Argentina) in a modified version of the American Academy of Pediatrics Neonatal Resuscitation Program (which teaches basic resuscitation in depth). The Essential Newborn Care intervention was assessed among 57,643 infants with the use of a before-and-after design. The Neonatal Resuscitation Program intervention was assessed as a cluster-randomized, controlled trial involving 62,366 infants. The primary outcome was neonatal death in the first 7 days after birth. RESULTS: The 7-day follow-up rate was 99.2%. After birth attendants were trained in the Essential Newborn Care course, there was no significant reduction from baseline in the rate of neonatal death from all causes in the 7 days after birth (relative risk with training, 0.99; 95% confidence interval [CI], 0.81 to 1.22) or in the rate of perinatal death; there was a significant reduction in the rate of stillbirth (relative risk with training, 0.69; 95% CI, 0.54 to 0.88; P=0.003). In clusters of births in which attendants had been randomly assigned to receive training in the Neonatal Resuscitation Program, as compared with control clusters, there was no reduction in the rates of neonatal death in the 7 days after birth, stillbirth, or perinatal death. CONCLUSIONS: The rate of neonatal death in the 7 days after birth did not decrease after the introduction of Essential Newborn Care training of community-based birth attendants, although the rate of stillbirths was reduced. Subsequent training in the Neonatal Resuscitation Program did not significantly reduce the mortality rates. (ClinicalTrials.gov number, NCT00136708.)
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Massachusetts Medical Society
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
newborn care
dc.subject
perinatal mortality
dc.subject.classification
Pediatría
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Medicina Clínica
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CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Newborn-Care Training and Perinatal Mortality in Developing Countries
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
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info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-03-04T17:30:56Z
dc.journal.volume
362
dc.journal.number
7
dc.journal.pagination
614-623
dc.journal.pais
Estados Unidos
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dc.description.fil
Fil: Carlo, Waldemar A.. University of Alabama at Birmingahm; Estados Unidos
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Fil: Goudar, Shivaprasad S.. Instituto de Efectividad Clínica y Sanitaria; Argentina
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Fil: Jehan, Imtiaz. Aga Khan University; Pakistán
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Fil: Chomba, Elwyn. Instituto de Efectividad Clínica y Sanitaria; Argentina
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Fil: Tshefu, Antoinette. No especifíca;
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Fil: Garces, Ana. Universidad de San Carlos ; Guatemala
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Fil: Sailajanandan, Parida. Sriramchandra Bhanja Medical College; India
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Fil: Althabe, Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina
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Fil: McClure, Elizabeth M.. No especifíca;
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Fil: Derman, Richard J.. University of Missouri; Estados Unidos
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Fil: Goldenberg, Robert L.. Drexel University College of Medicine; Estados Unidos
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Fil: Bose, Carl. University of North Carolina; Estados Unidos
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Fil: Krebs, Nancy F.. University of Colorado; Estados Unidos
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Fil: Panigrahi, Pinaki. No especifíca;
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Fil: Buekens, Pierre. Tulane School of Public Health and Tropical Medicine; Estados Unidos
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Fil: Chakraborty, Hrishikesh. No especifíca;
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Fil: Hartwell, Tyler D.. No especifíca;
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Fil: Wright, Linda L.. National Institute of Child Health and Human Development; Estados Unidos
dc.journal.title
New England Journal of Medicine
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1056/NEJMsa0806033
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.nejm.org/doi/full/10.1056/NEJMsa0806033
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