Mostrar el registro sencillo del ítem
dc.contributor.author
Galanternik, Fernando
dc.contributor.author
Recondo, Gonzalo
dc.contributor.author
Valsecchi, Matías E.
dc.contributor.author
Greco, Martín
dc.contributor.author
de la Vega, Máximo
dc.contributor.author
Cantón, E. Diaz
dc.date.available
2020-06-03T13:50:31Z
dc.date.issued
2016-06
dc.identifier.citation
Galanternik, Fernando; Recondo, Gonzalo; Valsecchi, Matías E.; Greco, Martín; de la Vega, Máximo; et al.; What is the current role of immunotherapy for colon cancer?; Bentham Science Publishers; Reviews on Recent Clinical Trials; 11; 2; 6-2016; 93-98
dc.identifier.issn
1574-8871
dc.identifier.uri
http://hdl.handle.net/11336/106569
dc.description.abstract
Colon cancer is a leading cause of cancer related mortality. Until very recently the only existing options that medical oncologists had to treat metastatic colon cancer were a combination of chemotherapy, anti-EGFR and anti-angiogenic agents. We currently have the first proof that immune therapies could be an effective approach to battle colorectal cancers that carry a mismatch repair machinery deficient phenotype. It is expected that as our knowledge of the different mechanisms of immune-resistance grows, this therapeutic modality might soon be applicable to all patients. However, due to the continuous increase in the cost of oncological drugs, some treatment overheads may soon become prohibitive for many. In this review we will examine the current evidence related to this topic with the objective to provide the reader with concise but practical information about the potential role of immunotherapy in CRC.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Bentham Science Publishers
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
COLON CANCER
dc.subject
LYNCH SYNDROME
dc.subject
MICROSATELLITE INSTABILITY
dc.subject
PD-1 BLOCKAGE
dc.subject
PEMBROLIZUMAB
dc.subject.classification
Oncología
dc.subject.classification
Medicina Clínica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
What is the current role of immunotherapy for colon cancer?
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-06-02T20:41:29Z
dc.identifier.eissn
1876-1038
dc.journal.volume
11
dc.journal.number
2
dc.journal.pagination
93-98
dc.journal.pais
Estados Unidos
dc.description.fil
Fil: Galanternik, Fernando. Centro de Educación Medica E Invest.clinicas; Argentina
dc.description.fil
Fil: Recondo, Gonzalo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Educación Medica E Invest.clinicas; Argentina
dc.description.fil
Fil: Valsecchi, Matías E.. No especifíca;
dc.description.fil
Fil: Greco, Martín. Centro de Educación Medica E Invest.clinicas; Argentina
dc.description.fil
Fil: de la Vega, Máximo. Fundacion Para Combatir la Leucemia; Argentina
dc.description.fil
Fil: Cantón, E. Diaz. Centro de Educación Medica E Invest.clinicas; Argentina. Fundacion Para Combatir la Leucemia; Argentina
dc.journal.title
Reviews on Recent Clinical Trials
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2174/1574887111666160330121851
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/140785/article
Archivos asociados