Artículo
Improvement in poly(ɛ-caprolactone) bio-activity: Structural characterization and in vitro assessment
Fecha de publicación:
07/01/2019
Editorial:
Taylor & Francis As
Revista:
International Journal Of Polymeric Materials
ISSN:
0091-4037
e-ISSN:
1563-535X
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Model PCL homopolymers (anionic polymerization) were synthetized and chemically functionalized with anhydrides to improve their bio-activity. Modified polyesters were used to fabricate highly porous PCL membranes by leaching technique, reaching porosities values up to 86.1%. Microstructural characterization revealed that chemical modification did not affect thermal properties and mechanical stabilities of PCL membranes. In vitro assays were carried out by soaking samples in simulated body fluid (SBF) solution. By SEM-EDX and TGA analyses, it was observed thatmodified polyesters exhibited a hydroxyapatite layer over polymeric surfaces, with calcium/phosphorous ratio of 1.58, close to the value reported by literature for hard tissue.
Palabras clave:
PCL
,
ANHYDRIDES
,
MODIFICATION
,
BIO-ACTIVITY
,
CHEMICAL FUNCTIONALIZATION
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(PLAPIQUI)
Articulos de PLANTA PILOTO DE INGENIERIA QUIMICA (I)
Articulos de PLANTA PILOTO DE INGENIERIA QUIMICA (I)
Citación
Ninago, Mario Daniel; Ciolino, Andrés Eduardo; Villar, Marcelo Armando; Improvement in poly(ɛ-caprolactone) bio-activity: Structural characterization and in vitro assessment; Taylor & Francis As; International Journal Of Polymeric Materials; 69; 4; 7-1-2019; 201-210
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