Effect of the urease-derived peptide Jaburetox on the central nervous system of Triatoma infestans (Insecta: Heteroptera)

Triatoma infestans is the main vector of Chagas'disease in Southern Cone countries. In triatomines, symptoms suggesting neurotoxicity were observed after treatment with Jaburetox (Jbtx), the entomotoxic peptide obtained from jackbean urease. Here, we study its effect in the central nervous system (CNS) of this species.

Palabras clave: Triatoma Infestans , Central Nervous Systm , Canavalia Ensiformis , Urease Udp-N-Acetylglucosaminepyrophosphorylase , Nitric Oxide

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Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Atribución-NoComercial-SinDerivadas 2.5 Argentina (CC BY-NC-ND 2.5 AR)

Identificadores

URI: http://hdl.handle.net/11336/10184

DOI: http://www.dx.doi.org/10.1016/j.bbagen.2014.11.008

URL: http://www.sciencedirect.com/science/article/pii/S0304416514003857

Colecciones

Articulos(CIBICI)
Articulos de CENTRO DE INV.EN BIOQUI.CLINICA E INMUNOLOGIA

Articulos(IBYME)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)

Citación

Galvani, Gerónimo Luis; Fruttero, Leonardo Luis; Coronel, Maria Florencia; Nowicki, Susana; Demartini, Diogo R.; et al.; Effect of the urease-derived peptide Jaburetox on the central nervous system of Triatoma infestans (Insecta: Heteroptera); Elsevier Science; Biochimica Et Biophysica Acta- General Subjects; 1850; 2; 2-2015; 255-262

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