Artículo
Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells
Labovsky, Vivian
; Martinez, Leandro Marcelo
; Davies, Kevin Mauro; García Rivello, Hernán; Calcagno, María de Luján; Matas, Ayelen; Fernández Vallone, Valeria Beatriz
; Wernicke, Alejandra; Choi, Hosoon; Chasseing, Norma Alejandra




Fecha de publicación:
02/2015
Editorial:
Elsevier
Revista:
Clinical Breast Cancer
ISSN:
1526-8209
e-ISSN:
1938-0666
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Despite advances in the study of breast cancer (BC), it remains the second leading cause of mortality among women. BC is a heterogeneous system, mainly composed of tumor epithelial cells (TEpCs) and stromal cells (SCs); the interaction through the ligands and their receptors (Rs) plays a major role in BC progression. The aim of the present study was to evaluate the association between ligands, such as osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), receptor activator of nuclear factor kappa B ligand (RANKL), stromal cell-derived factor (SDF)-1, interleukin (IL)-6, macrophage colony stimulating factor, chemokine (C-C motif) ligand-2 (CCL-2), and their Rs in TEpC and spindle-shaped SCs not closely associated with the vasculature.
Palabras clave:
Breast Cancer
,
Tumor Epithelial Cells
,
Stromal Cells
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Articulos(IBYME)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Citación
Labovsky, Vivian; Martinez, Leandro Marcelo; Davies, Kevin Mauro; García Rivello, Hernán; Calcagno, María de Luján; et al.; Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells; Elsevier; Clinical Breast Cancer; 15; 1; 2-2015; e13-e21
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