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dc.contributor.author
García, Adolfo Martín  
dc.contributor.author
Ibañez, Agustin Mariano  
dc.date.available
2020-03-20T18:05:33Z  
dc.date.issued
2014-05  
dc.identifier.citation
García, Adolfo Martín; Ibáñez Barassi, Agustín Mariano; Words in motion: Motor-language coupling in Parkinson's disease; Springer; Translational Neuroscience; 5; 2; 5-2014; 152-159  
dc.identifier.issn
2081-3856  
dc.identifier.uri
http://hdl.handle.net/11336/100429  
dc.description.abstract
A growing body of evidence indicates that neurodegenerative motor disorders involved high-order cognitive dysfunctions. Crucially, evidence obtained in multiple behavioral, neuroimaging, and electrophysiological studies points to selective impairments of action language -that is, processing of linguistic stimuli denoting motor actions, including idioms (e.g., cut a rug) and action verbs (e.g., clap). Action-verb deficits (with relative preservation of noun processing) have been repeatedly documented in Parkinson's disease (PD). However, research on relevant biomarkers is still scant, and clinical implications of these findings have not yet been formally discussed. Relevant insights may be obtained through the assessment of motor-language coupling (i.e., the behavioral and neural integration of action-verb processing and ongoing motor actions). We propose that motorlanguage coupling deficits, as indexed by a cortical-subcortical network, may constitute an early neurocognitive marker of PD. Specifically, deficits in this domain at the prodromal stage may be detected through the actionsentence compatibility (ACE) paradigm, which induces a contextual coupling of ongoing motor actions and action-verb processing. Our translational proposal is supported and illustrated by recent studies demonstrating the sensitivity of the ACE technique as well as its potential to assist in differential diagnosis and interventionprogram design.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Springer  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
MOTOR-LANGUAGE COUPLING  
dc.subject
NEUROLINGUISTICS  
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PARKINSON'S DISEASE  
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VERB-PROCESSING  
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Lingüística  
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Lengua y Literatura  
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HUMANIDADES  
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Psicología especial  
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Psicología  
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CIENCIAS SOCIALES  
dc.title
Words in motion: Motor-language coupling in Parkinson's disease  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2020-03-13T13:36:47Z  
dc.identifier.eissn
2081-6936  
dc.journal.volume
5  
dc.journal.number
2  
dc.journal.pagination
152-159  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Nueva York  
dc.description.fil
Fil: García, Adolfo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina  
dc.description.fil
Fil: Ibáñez Barassi, Agustín Mariano. Universidad Autónoma del Caribe; Colombia. Australian Research Council; Australia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Diego Portales; Chile  
dc.journal.title
Translational Neuroscience  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.2478/s13380-014-0218-6  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2478/s13380-014-0218-6