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dc.contributor.author
Albertini, Ricardo A.  
dc.contributor.author
Ferrer, Dario German  
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Romagnoli, Pablo A.  
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Tinti, María E.  
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Amigone, José L.  
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Capra, Raúl  
dc.contributor.author
Chiabrando, Gustavo Alberto  
dc.date.available
2018-06-11T14:03:38Z  
dc.date.issued
2017-05  
dc.identifier.citation
Albertini, Ricardo A.; Ferrer, Dario German; Romagnoli, Pablo A.; Tinti, María E.; Amigone, José L.; et al.; Association between cardiovascular disease risk scores and subclinical atherosclerosis prevalence in non-elderly adult patients from Argentina; Springer; International Journal Of Cardiovascular Imaging; 33; 10; 5-2017; 1-9  
dc.identifier.issn
1569-5794  
dc.identifier.uri
http://hdl.handle.net/11336/48050  
dc.description.abstract
The goal of our study was to use statistical analysis to try to associate cardiovascular disease (CVD) risk scores and the observed prevalence of subclinical atherosclerosis (SA) in a non-elderly adult local population. An observational cross-sectional study was carried out (143 male and 131 female) on non-elderly adults (20?59 years). CVD risk scores included Framingham Risk Scores for 10-year hard (FRS 10 H), 30-year lipid hard or CVD (FRS 30 L H or FRS 30 L CVD), 30 year-body mass index hard or CVD (FRS 30 BMI H or FRS 30 BMI CVD) and Pooled Cohort Risk Equations for either 10 years (PCE 10) or lifetime (PCE LT). The Carotid Ultrasound (CU) study was performed and the Coronary Artery Calcium (CAC) score were obtained to assess SA. The Receiving Operating Characteristic (ROC) curve analysis followed by Youden?s index was used to evaluate and adjust the stratification of CVD risk scores. SA was detected in 32.4% of individuals. The risk scores that showed the biggest areas under the ROC curve were FRS 30 L (H and CVD). When the cut-off values for these CVD risk scores were adjusted, the FRS 30 L H increased the negative predictive value for the low risk group from 87.7 to 97.0% and the FRS 30 L CVD increased the positive predictive values for the high risk group from 69.7 to 85.7%. The CVD risk stratification of non-elderly adults using FRS 30 L H and FRS 30 L CVD may be a useful tool for selecting candidate patients for diagnostic imaging studies that assess their SA prevalence.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Springer  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Argentina  
dc.subject
Cardiovascular Disease  
dc.subject
Framingham Risk Scores  
dc.subject
Pooled Cohort Equations  
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Subclinical Atherosclerosis  
dc.subject.classification
Otras Ciencias Biológicas  
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Ciencias Biológicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Association between cardiovascular disease risk scores and subclinical atherosclerosis prevalence in non-elderly adult patients from Argentina  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-05-30T18:21:51Z  
dc.identifier.eissn
1573-0743  
dc.journal.volume
33  
dc.journal.number
10  
dc.journal.pagination
1-9  
dc.journal.pais
Alemania  
dc.description.fil
Fil: Albertini, Ricardo A.. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina. Hospital Privado Centro Medico de Córdoba; Argentina  
dc.description.fil
Fil: Ferrer, Dario German. Hospital Privado Centro Medico de Córdoba; Argentina  
dc.description.fil
Fil: Romagnoli, Pablo A.. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina  
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Fil: Tinti, María E.. Hospital Privado Centro Medico de Córdoba; Argentina  
dc.description.fil
Fil: Amigone, José L.. Hospital Privado Centro Medico de Córdoba; Argentina  
dc.description.fil
Fil: Capra, Raúl. Hospital Privado Centro Medico de Córdoba; Argentina  
dc.description.fil
Fil: Chiabrando, Gustavo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina  
dc.journal.title
International Journal Of Cardiovascular Imaging  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s10554-017-1152-9  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://bit.ly/2Mf5XGG