Mostrar el registro sencillo del ítem

dc.contributor.author
Rahn, Irene Monica  
dc.contributor.author
Noronha, Renata C.  
dc.contributor.author
Nagamachi, Cleusa Y.  
dc.contributor.author
Pieczarka, Julio C.  
dc.contributor.author
Solari, Alberto Juan  
dc.contributor.author
Sciurano, Roberta Beatriz  
dc.date.available
2018-03-14T18:05:00Z  
dc.date.issued
2016-09  
dc.identifier.citation
Rahn, Irene Monica; Noronha, Renata C.; Nagamachi, Cleusa Y.; Pieczarka, Julio C.; Solari, Alberto Juan; et al.; Protein markers of synaptic behavior and chromatin remodeling of the neo-XY body in phyllostomid bats; Springer; Chromosoma; 125; 4; 9-2016; 701-708  
dc.identifier.issn
0009-5915  
dc.identifier.uri
http://hdl.handle.net/11336/38751  
dc.description.abstract
The XX/XY system is the rule among mammals. However, many exceptions from this general pattern have been discovered since the last decades. One of these non-conventional sex chromosome mechanisms is the multiple sex chromosome system, which is evolutionary fixed among many bat species of the family Phyllostomidae, and has arisen by a translocation between one original gonosome (X or Y chromosome), and an autosome, giving rise to a “neo-XY body.” The aim of this work is to study the synaptic behavior and the chromatin remodeling of multiple sex chromosomes in different species of phyllostomid bats using electron microscopy and molecular markers. Testicular tissues from adult males of the species Artibeus lituratus, Artibeus planirostris, Uroderma bilobatum, and Vampyrodes caraccioli from the eastern Amazonia were analyzed by optical/electron microscopy and immunofluorescence of meiotic proteins involved in synapsis (SYCP3 and SYCE3), sister-chromatid cohesion (SMC3), and chromatin silencing (BRCA1, γ-H2AX, and RNApol 2). The presence of asynaptic axes—labeled by BRCA1 and γ-H2AX—at meiotic prophase in testes that have a normal development of spermatogenesis, suggests that the basic mechanism that arrests spreading of transcriptional silencing (meiotic sex chromosome inactivation (MSCI)) to the autosomal segments may be per se the formation of a functional synaptonemal complex between homologous or non-homologous regions, and thus, this SC barrier might be probably related to the preservation of fertility in these systems.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Springer  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Bats  
dc.subject
Chromatin Remodeling  
dc.subject
Gonosome-Autosome Systems  
dc.subject
Meiosis  
dc.subject
Spermatogenesis  
dc.subject.classification
Otras Ciencias Biológicas  
dc.subject.classification
Ciencias Biológicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Protein markers of synaptic behavior and chromatin remodeling of the neo-XY body in phyllostomid bats  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-03-14T17:03:35Z  
dc.identifier.eissn
1432-0886  
dc.journal.volume
125  
dc.journal.number
4  
dc.journal.pagination
701-708  
dc.journal.pais
Alemania  
dc.journal.ciudad
Berlin  
dc.description.fil
Fil: Rahn, Irene Monica. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Noronha, Renata C.. Universidade Federal do Pará; Brasil  
dc.description.fil
Fil: Nagamachi, Cleusa Y.. Universidade Federal do Pará; Brasil  
dc.description.fil
Fil: Pieczarka, Julio C.. Universidade Federal do Pará; Brasil  
dc.description.fil
Fil: Solari, Alberto Juan. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Sciurano, Roberta Beatriz. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.journal.title
Chromosoma  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s00412-015-0566-1  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs00412-015-0566-1