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dc.contributor.author
Bezrodnik, Liliana  
dc.contributor.author
Di Giovanni, Daniela  
dc.contributor.author
Caldirola, María Soledad  
dc.contributor.author
Esnaola Azcoiti, María  
dc.contributor.author
Torgerson, Troy  
dc.contributor.author
Gaillard, María Isabel  
dc.date.available
2018-03-09T18:42:17Z  
dc.date.issued
2015-03  
dc.identifier.citation
Bezrodnik, Liliana; Di Giovanni, Daniela; Caldirola, María Soledad; Esnaola Azcoiti, María; Torgerson, Troy; et al.; Long-Term Follow-up of STAT5B Deficiency in Three Argentinian Patients: Clinical and Immunological Features; Springer/Plenum Publishers; Journal of Clinical Immunology; 35; 3; 3-2015; 264-272  
dc.identifier.issn
0271-9142  
dc.identifier.uri
http://hdl.handle.net/11336/38427  
dc.description.abstract
The signal transducer and activator of transcription (STAT) family of proteins regulate gene transcription in response to a variety of cytokines. STAT5B, in particular, plays an important role in T cells, where it is a key mediator of interleukin-2 (IL-2) induced responses. STAT5B deficiency causes a rare autosomal recessive disorder reported in only a handful of individuals. There are currently ten published cases of STAT5B deficiency, four of which are Argentinians.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Springer/Plenum Publishers  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Dysregulatory Syndrome  
dc.subject
Growth Hormone  
dc.subject
Lymphocytic Interstitial Pneumonitis  
dc.subject
Primary Immunodeficiency  
dc.subject
Regulatory T Cells  
dc.subject
Stat5b  
dc.subject.classification
Inmunología  
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Medicina Básica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Long-Term Follow-up of STAT5B Deficiency in Three Argentinian Patients: Clinical and Immunological Features  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-03-09T14:43:56Z  
dc.journal.volume
35  
dc.journal.number
3  
dc.journal.pagination
264-272  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Nueva York  
dc.description.fil
Fil: Bezrodnik, Liliana. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Di Giovanni, Daniela. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina  
dc.description.fil
Fil: Caldirola, María Soledad. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina  
dc.description.fil
Fil: Esnaola Azcoiti, María. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina  
dc.description.fil
Fil: Torgerson, Troy. University of Washington; Estados Unidos  
dc.description.fil
Fil: Gaillard, María Isabel. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina  
dc.journal.title
Journal of Clinical Immunology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs10875-015-0145-5  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s10875-015-0145-5  

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