Artículo
Ex Vivo Loading of Autologous Dendritic Cells with Tumor Antigens
Fecha de publicación:
02/2014
Editorial:
Springer
Revista:
Methods in Molecular Biology (clifton, N.j.)
ISSN:
1064-3745
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Ex vivo-generated antigen-loaded dendritic cells (DC) have been shown to be immunogenic in patients with cancer. Loading DC with autologous whole tumor antigens is a strategy to arm DC against tumor without human leukocyte antigen (HLA) restriction. Furthermore, this approach allows the presentation of a full antigen range to the immune system. We describe the methods to obtain whole antigens from autologous tumor tissues in order to load DC generated ex vivo from patients with gastrointestinal cancer.
Palabras clave:
Dendritic Cells
,
Cancer
,
Vaccines
,
Protocol
,
Tumor Specimen
,
Autologous Tumor Tissue
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Identificadores
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Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Articulos de SEDE CENTRAL
Citación
Rizzo, Manglio Miguel; Alaniz, Laura Daniela; Mazzolini Rizzo, Guillermo Daniel; Ex Vivo Loading of Autologous Dendritic Cells with Tumor Antigens; Springer; Methods in Molecular Biology (clifton, N.j.); 2-2014; 41-44
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