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dc.contributor.author
Pou, Sonia Alejandra
dc.contributor.author
Diaz, Maria del Pilar
dc.contributor.author
Osella, Alberto Rubén
dc.date.available
2023-05-15T16:54:59Z
dc.date.issued
2012-09
dc.identifier.citation
Pou, Sonia Alejandra; Diaz, Maria del Pilar; Osella, Alberto Rubén; Applying multilevel model to the relationship of dietary patterns and colorectal cancer: An ongoing case-control study in Córdoba, Argentina; Dr. Dietrich Steinkopff Verlag; European Journal of Nutrition; 51; 6; 9-2012; 755-764
dc.identifier.issn
1436-6207
dc.identifier.uri
http://hdl.handle.net/11336/197568
dc.description.abstract
Scientific literature has consistently shown the effects of certain diets on health but regional variations of dietary habits, and their relationship colorectal cancer (CRC) has been poorly studied in Argentina. Our aims were to identify dietary patterns and estimate their effect on CRC occurrence and to quantify the association between family history of CRC and CRC occurrence by applying multilevel models to estimate and interpret measures of variation. Methods: Principal components factor analysis was performed to identify dietary patterns that were then used in a multilevel logistic regression applied to an ongoing case-control data about dietary exposure and CRC occurrence taking into account familiar clustering. Results: Three dietary patterns were identified: "Southern Cone pattern" (red meat, wine, and starchy vegetables), "High-sugar drinks pattern", and "Prudent pattern". The study considered 41 cases and 95 controls. There was a significant promoting effects on CRC of "Southern Cone" (OR 1.5, 95%CI 1.0-2.2) and "High-sugar drinks" (OR 3.8, 95%CI 2.0-7.1) patterns, whereas "Prudent pattern" (OR 0.3, 95%CI 0.2-0.4) showed a significant protective effect at third tertile level. BMI, use of NSAIDs, and to have medical insurance showed significant effects. Variance of the random effect of family history of CRC was highly significant. Conclusions: This novel approach for Argentina showed that Southern Cone and High-sugar drinks patterns were associated with a higher risk of CRC, whereas the Prudent pattern showed a protective effect. There was a significant clustering effect of family history of CRC.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Dr. Dietrich Steinkopff Verlag
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
ARGENTINA
dc.subject
COLORECTAL CANCER
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DIETARY PATTERNS
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MEAT INTAKE
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MULTILEVEL
dc.subject.classification
Nutrición, Dietética
dc.subject.classification
Ciencias de la Salud
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Applying multilevel model to the relationship of dietary patterns and colorectal cancer: An ongoing case-control study in Córdoba, Argentina
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-05-12T10:14:20Z
dc.identifier.eissn
1436-6215
dc.journal.volume
51
dc.journal.number
6
dc.journal.pagination
755-764
dc.journal.pais
Alemania
dc.description.fil
Fil: Pou, Sonia Alejandra. Universidad Nacional de Córdoba. Facultad de Medicina. Escuela de Nutrición. Cátedra de Estadística y Bioestadística; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
dc.description.fil
Fil: Diaz, Maria del Pilar. Universidad Nacional de Córdoba. Facultad de Medicina. Escuela de Nutrición; Argentina
dc.description.fil
Fil: Osella, Alberto Rubén. Universidad Nacional de Córdoba. Facultad de Medicina. Escuela de Nutrición. Cátedra de Estadística y Bioestadística; Argentina
dc.journal.title
European Journal of Nutrition
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s00394-011-0255-7
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007/s00394-011-0255-7
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