Artículo
Staphylococcus aureus Potentiates the Hemolytic Activity of Burkholderia cepacia Complex (Bcc) Bacteria
Moriano, Alessandro; Serra, Diego Omar
; Hoard, Amparo; Montaña, Sabrina Daiana
; Degrossi, Jose; Bonomo, Robert A.; Papp-Wallace, Krisztina M.; Ramirez, Maria Soledad
Fecha de publicación:
05/2021
Editorial:
Springer
Revista:
Current Microbiology
ISSN:
0343-8651
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Polymicrobial lung infections in individuals with Cystic Fibrosis (CF) contribute to the complexity of this disease and are a major cause of morbidity and mortality in the CF community. The microorganisms most commonly associated with severe airway infections in individuals with CF are the opportunistic pathogens S. aureus, P. aeruginosa and bacteria from the Burkholderia cepacia complex (Bcc), particularly B. cenocepacia and B. multivorans. Three Bcc strains, two S. aureus wild-type strains, and two derivative mutants were used to investigate the interplay between S. aureus and Bcc with a focus on the hemolytic activity of Bcc. Our results revealed that extracellular products from S. aureus potentiated the hemolysis of Bcc strains. Moreover, this effect was influenced by the composition of the medium in which S. aureus is grown. These findings contribute towards the understanding of the impact of interactions between S. aureus and Bcc and their possible implications in the context of co-infections by these pathogens in individuals with CF.
Palabras clave:
POLYMICROBIAL INFECTIONS
,
CYSTIC FIBROSIS PATHOGENS
,
BIOFILM
,
HEMOLYSIS
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(IBR)
Articulos de INST.DE BIOLOGIA MOLECULAR Y CELULAR DE ROSARIO
Articulos de INST.DE BIOLOGIA MOLECULAR Y CELULAR DE ROSARIO
Citación
Moriano, Alessandro; Serra, Diego Omar; Hoard, Amparo; Montaña, Sabrina Daiana; Degrossi, Jose; et al.; Staphylococcus aureus Potentiates the Hemolytic Activity of Burkholderia cepacia Complex (Bcc) Bacteria; Springer; Current Microbiology; 78; 5; 5-2021; 1864-1870
Compartir
Altmétricas