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dc.contributor.author
Ronderos, Ricardo
dc.contributor.author
Politi, Teresa
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Mahia, Mariana Cecilia
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Castro, María Florencia
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Sciancalepore, Agustina
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Cueva Torres, Franklin
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Kuschnir, Paola
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de la Paz Ricapito, María
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Vrancic, Juan Mariano
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Camporrotondo, Mariano
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Piccinini, Fernando
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Navia, Daniel
dc.date.available
2022-10-06T16:59:30Z
dc.date.issued
2021-06
dc.identifier.citation
Ronderos, Ricardo; Politi, Teresa; Mahia, Mariana Cecilia; Castro, María Florencia; Sciancalepore, Agustina; et al.; Hemodynamically significant prosthesis-patient mismatch can be predicted and is associated with early prosthetic valve dysfunction in aortic bioprosthesis; Wiley Blackwell Publishing, Inc; Echocardiography; 38; 6; 6-2021; 814-824
dc.identifier.issn
1540-8175
dc.identifier.uri
http://hdl.handle.net/11336/172287
dc.description.abstract
Objectives: To evaluate the accuracy of predicted prosthesis-patient mismatch (PPM) regarding actual PPM measured postoperatively. To assess the association between PPM and prosthetic valve dysfunction. Methods: Retrospective cohort study including adult patients after aortic valve replacement surgery with a biological prosthesis. Predicted PPM status was determined using mean reference effective orifice area indexed to total body surface (iEOA), without considering reference standard deviations. Postoperative PPM status was determined by measuring iEOA within the first 60 postoperative days. Prosthetic valve dysfunction was defined as thrombosis, pannus, valve degeneration, and/or disruption. Results: 205 patients were enrolled between January 2003 and June 2017: predicted PPM was absent in 52 patients (25.4%), moderate in 137 patients (66.8%), and severe in 16 patients (7.8%). After surgery, the actual postoperative iEOA was measured: 53 (25.9%) did not have PPM, 73 had moderate PPM (35.6%), and 79 had severe PPM (38.5%). Predicted PPM identified the presence of hemodynamically significant actual postoperative PPM (OR = 2.56; 95%CI 1.30–5.05; P =.006), though not its degree of severity. Prosthetic valve dysfunction was more frequent among patients with hemodynamically significant PPM (53.9% vs. 11.3%; P <.001), compared to those without PPM. The association between PPM and prosthetic valve dysfunction was maintained after adjusting for gender, age, and ever-smoking (OR = 9.03; P <.001). The incidence of thrombosis or pannus was also nonsignificantly higher in patients with moderate or severe PPM. Conclusions: Predicted PPM identifies the presence, possibly not the severity, of actual postoperative PPM. Moderate or severe PPM is associated with prosthetic valve dysfunction. Actual postoperative prosthesis-patient mismatch measured within 60 postoperative days showed a distinctive hemodynamic profile and presented a stronger association with prosthetic valve dysfunction than predicted prosthesis-patient mismatch. A. Echocardiographic follow-up in patients according to the actual postoperative PPM measured within 60 postoperative days. B. Prediction of prosthetic valve dysfunction based on preoperative predicted PPM or on actual postoperative PPM within 60 postoperative days. PPM: prosthesis-patient mismatch. OR: Odds ratio.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley Blackwell Publishing, Inc
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
AORTIC VALVE PROSTHESIS
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AORTIC VALVE REPLACEMENT
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CARDIAC SURGERY
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DOPPLER ECHOCARDIOGRAPHY
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THROMBUS
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Sistemas Cardíaco y Cardiovascular
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Medicina Clínica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Hemodynamically significant prosthesis-patient mismatch can be predicted and is associated with early prosthetic valve dysfunction in aortic bioprosthesis
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-09-20T15:45:37Z
dc.journal.volume
38
dc.journal.number
6
dc.journal.pagination
814-824
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Ronderos, Ricardo. Instituto Cardiovascular de Buenos Aires; Argentina
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Fil: Politi, Teresa. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiología y Biofísica Bernardo Houssay; Argentina
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Fil: Mahia, Mariana Cecilia. Instituto Cardiovascular de Buenos Aires; Argentina
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Fil: Castro, María Florencia. Instituto Cardiovascular de Buenos Aires; Argentina
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Fil: Sciancalepore, Agustina. Instituto Cardiovascular de Buenos Aires; Argentina
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Fil: Cueva Torres, Franklin. Instituto Cardiovascular de Buenos Aires; Argentina
dc.description.fil
Fil: Kuschnir, Paola. Instituto Cardiovascular de Buenos Aires; Argentina
dc.description.fil
Fil: de la Paz Ricapito, María. Instituto Cardiovascular de Buenos Aires; Argentina
dc.description.fil
Fil: Vrancic, Juan Mariano. Instituto Cardiovascular de Buenos Aires; Argentina
dc.description.fil
Fil: Camporrotondo, Mariano. Instituto Cardiovascular de Buenos Aires; Argentina
dc.description.fil
Fil: Piccinini, Fernando. Instituto Cardiovascular de Buenos Aires; Argentina
dc.description.fil
Fil: Navia, Daniel. Instituto Cardiovascular de Buenos Aires; Argentina
dc.journal.title
Echocardiography
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/echo.15068
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1111/echo.15068
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