Capítulo de Libro
Recent advances in the solid-phase synthesis of N-heteroaromatic five membered rings
Título del libro: Modern Approaches to the Synthesis of O- and N-Heterocycles
Fecha de publicación:
2007
Editorial:
Research Signpost
ISBN:
978-81-308-0165-0
Idioma:
Inglés
Clasificación temática:
Resumen
Combinatorial chemistry and related high-speed syntheses are powerful tools for the discovery of new drugs. In particular, solid-phase organic synthesis (SPOS) is being widely used for the preparation of a large number of structurally diverse small organic molecules in order to accelerate lead generation and optimization. Due to their potential biological activities, the synthesis of five-membered ring heteroaromatics is of great importance in medicinal chemistry. Consequently, different solid-phase approaches for the preparation of these heterocycles have been recently introduced. This chapter covers the syntheses of N-heteroaromatic five-membered rings that have been reported in the literature during the last seven years.
Palabras clave:
SOLID-PHASE
,
HETEROCYCLES
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Capítulos de libros(IQUIR)
Capítulos de libros de INST.DE QUIMICA ROSARIO
Capítulos de libros de INST.DE QUIMICA ROSARIO
Citación
Testero, Sebastian Andres; Poeylaut Palena, Andrés Alberto; Mata, Ernesto Gabino; Recent advances in the solid-phase synthesis of N-heteroaromatic five membered rings; Research Signpost; 2007; 341-372
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