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dc.contributor.author
Malanga, Gabriela Fabiana  
dc.contributor.author
Giarratano, Erica  
dc.contributor.author
Lores Arnaiz, Silvia  
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Puntarulo, Susana Ángela  
dc.contributor.author
Bustamante, Juanita  
dc.contributor.other
Brooke, M.  
dc.contributor.other
Grover, E.  
dc.date.available
2021-05-18T12:41:33Z  
dc.date.issued
2018  
dc.identifier.citation
Malanga, Gabriela Fabiana; Giarratano, Erica; Lores Arnaiz, Silvia; Puntarulo, Susana Ángela; Bustamante, Juanita; Hemocytes of the bivalve Aulacomya atra atra from Bahia Nueva (Chubut) as Biomarkers of Oxidative Stress; Nova Science Publishers; 2018; 123-154  
dc.identifier.isbn
978-1-53613-459-9  
dc.identifier.uri
http://hdl.handle.net/11336/132197  
dc.description.abstract
Bivalve mollusks exposed to a wide variety of natural and anthropogenic environmental changes are widely used as sentinels. These factors can cause an imbalance between the generation and elimination of reactive oxygen species (ROS) and reactive nitrogen species (RNS), leading to an oxidative stress that is manifested by alterations of the antioxidant defense system and/or oxidative damage. The hemocytes constitute the immune system in bivalves, and cell death processes have been recently described as part of the mechanism of defense against various pathogens and contaminants. Previous studies showed a higher content of trace metals Fe and Cd in the gills and digestive gland of the Aulacomya atra atra from Folías Wreck (impacted area) than from Punta Cuevas (control area). In order to compare oxidative stress conditions in bivalves obtained from both sites, we evaluated the production of ROS and oxidative stress biomarkers in hemocytes from the A. atra atra during the month of September of 2015. The results obtained by flow cytometry, using MitoSox as probe, showed that superoxide anion was 58% higher in bivalve’s hemocytes from Folías Wreck than in those from the reference place Punta Cuevas. The oxidation of the dye 2´7´dichlorofluorescein diacetate (DCFH-DA), as a general indicator of oxidative stress, showed a 14% increase in bivalve’s hemocytes from Folías Wreck, as compared to hemocytes from Punta Cuevas. Thiobarbituric acid reactive substances (TBARS) content showed no differences between hemocytes from animals isolated from both locations. In addition, the content of lipid radical measured by Electron Spin Resonance increased 2.1 fold in the hemocytes from Folías Wreck samples as compared to the level obtained in hemocytes from bivalves collected from Punta Cuevas. The oxidized/depleted cardiolipin was 16% higher in samples obtained from Folías Wreck than in Punta Cuevas. Based on these results, it can be concluded that hemocytes from the ribbed mussel A. atra atra could be used as a model to evaluate oxidative stress induced by pollutants or other environmental stressors.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Nova Science Publishers  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
HEMOCYTES  
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BIVALVES  
dc.subject
OXIDATIVE STRESS  
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BIOMARKERS  
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Bioquímica y Biología Molecular  
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Ciencias Biológicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Hemocytes of the bivalve Aulacomya atra atra from Bahia Nueva (Chubut) as Biomarkers of Oxidative Stress  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.type
info:eu-repo/semantics/bookPart  
dc.type
info:ar-repo/semantics/parte de libro  
dc.date.updated
2021-03-26T19:59:11Z  
dc.journal.pagination
123-154  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
New York  
dc.description.fil
Fil: Malanga, Gabriela Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina  
dc.description.fil
Fil: Giarratano, Erica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Centro para el Estudio de Sistemas Marinos; Argentina  
dc.description.fil
Fil: Lores Arnaiz, Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina  
dc.description.fil
Fil: Puntarulo, Susana Ángela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina  
dc.description.fil
Fil: Bustamante, Juanita. Universidad Abierta Interamericana; Argentina  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://novapublishers.com/shop/mussels-characteristics-biology-and-conservation/  
dc.conicet.paginas
300  
dc.source.titulo
Mussels: Characteristics, Biology and Conservation