Artículo

Proposing Kluyvera georgiana as the Origin of the Plasmid-Mediated Resistance Gene fosA4

Rodriguez, Maria MargaritaIcon ; Ghiglione, BarbaraIcon ; Power, PabloIcon ; Naas, Thierry; Gutkind, Gabriel OsvaldoIcon
Fecha de publicación: 08/2018
Editorial: American Society for Microbiology
Revista: Antimicrobial Agents and Chemotherapy
ISSN: 0066-4804
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

A putative fosA gene in Kluyvera georgiana 14751 showed 99% nucleotide identity with plasmid-encoded fosA4. Due to a single-nucleotide insertion translating to a truncated protein, K. georgiana 14751 fosA does not confer fosfomycin resistance. However, analysis of another genome deposit (Kluyvera ascorbata WCH1410) that could be recategorized as K. georgiana after phylogenetic analysis revealed a fosA gene 100% identical to the plasmid-borne fosA4 gene. We suggest that Kluyvera georgiana represents the most probable origin of fosA4.
Palabras clave: FOSA , FOSFOMYCIN RESISTANCE , KLUYVERA ASCORBATA , KLUYVERA GEORGIANA , WHOLE-GENOME SEQUENCING
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/99398
URL: http://aac.asm.org/lookup/doi/10.1128/AAC.00710-18
DOI: http://dx.doi.org/10.1128/AAC.00710-18
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Articulos(OCA HOUSSAY)
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Citación
Rodriguez, Maria Margarita; Ghiglione, Barbara; Power, Pablo; Naas, Thierry; Gutkind, Gabriel Osvaldo; Proposing Kluyvera georgiana as the Origin of the Plasmid-Mediated Resistance Gene fosA4; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 62; 8; 8-2018; 1-8
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