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dc.contributor.author
de Brun, V.  
dc.contributor.author
Abecia, J. A.  
dc.contributor.author
Fernandez Foren, A.  
dc.contributor.author
Carriquiry, M.  
dc.contributor.author
Forcada, F.  
dc.contributor.author
Vazquez, Maria Isabel  
dc.contributor.author
Meikle, A.  
dc.contributor.author
Sosa, C.  
dc.date.available
2016-12-20T21:10:28Z  
dc.date.issued
2013-04  
dc.identifier.citation
de Brun, V.; Abecia, J. A.; Fernandez Foren, A.; Carriquiry, M.; Forcada, F.; et al.; Undernutrition affects the local effect of the corpus luteum on gene expression of the oviduct and uterus in sheep; Spanish National Institute For Agriculture And Food Research And Technology; Spanish Journal Of Agricultural Research; 11; 4; 4-2013; 989-996  
dc.identifier.issn
1695-971X  
dc.identifier.uri
http://hdl.handle.net/11336/9869  
dc.description.abstract
The effect of undernutrition on gene expression of progesterone and oestrogen receptors (PGR and ESR1), and insulin-like growth factors 1 and 2 (IGF1 and IGF2) in the uterus and oviducts of ewes on day 5 after oestrus was investigated. The effect of the side of the uterus/oviduct regarding the ovary bearing a corpus luteum (CL) (ipsi vs. contralateral) was also analyzed. Fourteen oestrous synchronized ewes were fed either 1.5 (C, n=7) or 0.5 (L, n=7) times their maintenance requirements from the onset of the hormonal treatment (day -14), till slaughter on day 5 post-oestrus. Oviducts and samples of uterus were collected and their gene expression studied by real time RT-PCR. Undernourished ewes had greater PGR expression in the oviduct than control ewes, but lower expression of IGF1 in uterus and of IGF2 in oviducts. The ipsilateral oviduct presented lower expression of PGR, ESR1 and IGF2 mRNA than the contralateral one, but this did not occur in the uterus. In conclusion, there is an effect of undernutrition on gene expression that is transcript and organ dependent (uterus/oviduct). This work reports for the first time that growth factors and sex steroid receptor expression on day 5 after oestrus vary depending on the side of the CL-bearing ovary and the region of the reproductive tract.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Spanish National Institute For Agriculture And Food Research And Technology  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Nutrition  
dc.subject
Reproductive Tract  
dc.subject
Steroid Receptors  
dc.subject
Growth Factors  
dc.subject.classification
Ciencias Veterinarias  
dc.subject.classification
Ciencias Veterinarias  
dc.subject.classification
CIENCIAS AGRÍCOLAS  
dc.subject.classification
Ciencias Veterinarias  
dc.subject.classification
Ciencias Veterinarias  
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CIENCIAS AGRÍCOLAS  
dc.title
Undernutrition affects the local effect of the corpus luteum on gene expression of the oviduct and uterus in sheep  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2016-12-19T18:05:29Z  
dc.identifier.eissn
2171-9292  
dc.journal.volume
11  
dc.journal.number
4  
dc.journal.pagination
989-996  
dc.journal.pais
España  
dc.description.fil
Fil: de Brun, V.. Universidad de la Republica; Uruguay  
dc.description.fil
Fil: Abecia, J. A.. Universidad de Zaragoza; España  
dc.description.fil
Fil: Fernandez Foren, A.. Universidad de la Republica; Uruguay  
dc.description.fil
Fil: Carriquiry, M.. Universidad de la Republica; Uruguay  
dc.description.fil
Fil: Forcada, F.. Universidad de Zaragoza; España  
dc.description.fil
Fil: Vazquez, Maria Isabel. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; Argentina. Universidad de Zaragoza; España. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Meikle, A.. Universidad de la Republica; Uruguay  
dc.description.fil
Fil: Sosa, C.. Universidad de Zaragoza; España  
dc.journal.title
Spanish Journal Of Agricultural Research  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://revistas.inia.es/index.php/sjar/article/view/3912  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.5424/sjar/2013114-3912  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://dialnet.unirioja.es/servlet/articulo?codigo=4860633