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dc.contributor.author
Silveyra, María Ximena
dc.contributor.author
Lanteri, Maria Luciana
dc.contributor.author
Damiano, Rocío Belén
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Andreu, Adriana Balbina
dc.date.available
2019-10-28T17:17:26Z
dc.date.issued
2018-03-22
dc.identifier.citation
Silveyra, María Ximena; Lanteri, Maria Luciana; Damiano, Rocío Belén; Andreu, Adriana Balbina; Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro; Hindawi Limited; Journal of Nutrition and Metabolism; 22-3-2018; 1-10
dc.identifier.issn
2090-0724
dc.identifier.uri
http://hdl.handle.net/11336/87398
dc.description.abstract
Potatoes (Solanum tuberosum L.) are a good source of dietary antioxidant polyphenols. This study investigated the potential antioxidant, bactericidal and cytotoxic activities in vitro of the phenolic compounds present in tubers of one S. tuberosum spp tuberosum (Summerside) and three S. tuberosum spp andigena (landraces Moradita, Waicha, Santa María) cultivars. Both the content of phenolic acids, chlorogenic acids (CGAs) being the most abundant, and the antioxidant activity were higher in extracts from skin than from flesh. Extracts from Moradita flesh and Summerside skin showed bactericidal activity against Escherichia coli ATCC 25922 but failed to inhibit pathogenic E. coli O157. Both extracts lack pigmentation but do contain 5-CGA, caffeic and ferulic acids. Positive control with gentamicin and commercial 5-CGA resulted in a complete inhibition of bacterial growth. In addition, all potato extracts and commercial 5-CGA diminished dose-dependently Human neuroblastoma SH-SY5Y cell viability. Skin extracts were more potent than flesh extracts. Among flesh extracts, Moradita was the most potent. Together, our results suggest that Moradita flesh could provide a desirable source of important health-promoting substances. Findings indicate that the biological activity of potato extracts is a combination of various bioactive compounds and contribute to the revalorization of potato as a functional food.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Hindawi Limited
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
BACTERICIDAL
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CYTOTOXIC
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POLYPHENOL EXTRACTS
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SOLANUM TUBEROSUM SPP TUBEROSUM
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SOLANUM TUBEROSUM SPP ANDIGENA
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ESCHERICHIA COLI
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NEUROBLASTOMA SH-SY5Y
dc.subject.classification
Biología Celular, Microbiología
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-10-22T15:52:05Z
dc.journal.pagination
1-10
dc.journal.pais
Estados Unidos
dc.description.fil
Fil: Silveyra, María Ximena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; Argentina
dc.description.fil
Fil: Lanteri, Maria Luciana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; Argentina
dc.description.fil
Fil: Damiano, Rocío Belén. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
dc.description.fil
Fil: Andreu, Adriana Balbina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; Argentina
dc.journal.title
Journal of Nutrition and Metabolism
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/jnme/2018/8073679/
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1155/2018/8073679
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