Artículo
Anti-Infective Pregnane Steroid from the Octocoral Carijoa riisei Collected in South Brazil
Rojo de Almeida, Maria Tereza; Tonini, Maiko L.; Guimaraes, Tatiana; Bianco, Everson; Moritz, Maria I.; Oliveira, Simone; Cabrera, Gabriela Myriam
; Palermo, Jorge Alejandro
; Regginato, Flavio; Steindel, Mario; Schenkel, Eloir P.
![Icon](/themes/CONICETDigital/images/conicet.png)
![Icon](/themes/CONICETDigital/images/conicet.png)
Fecha de publicación:
11/2012
Editorial:
Colegio de Farmacéuticos de la Provincia de Buenos Aires
Revista:
Acta Farmacéutica Bonaerense
ISSN:
0326-2383
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
SUMMARY. In the present work, fractions of the ethanolic crude extract of Carijoa riisei (Octocorallia) collected at South Brazil (Santa Catarina island) were tested against different bacterial, fungal and protozoal pathogens. The n-hexane fraction (HF) showed a moderate activity against S. aureus in the disk diffusion method, and inhibited 43.4 and 35.9 % the growing of T. cruzi epimastigotes and L. braziliensis promastigotes, respectively. The steroid pregna-1,4,20-trien-3-one was isolated from HF and presented in vitro antiprotozoal activity against the extracellular forms of the parasites at 50 μM, showing 50.4 % growth inhibition of L. braziliensis and 42.4 % growth inhibition of T. cruzi.
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Identificadores
Colecciones
Articulos(UMYMFOR)
Articulos de UNID.MICROANAL.Y MET.FISICOS EN QUIM.ORG.(I)
Articulos de UNID.MICROANAL.Y MET.FISICOS EN QUIM.ORG.(I)
Citación
Rojo de Almeida, Maria Tereza; Tonini, Maiko L.; Guimaraes, Tatiana; Bianco, Everson; Moritz, Maria I.; et al.; Anti-Infective Pregnane Steroid from the Octocoral Carijoa riisei Collected in South Brazil; Colegio de Farmacéuticos de la Provincia de Buenos Aires; Acta Farmacéutica Bonaerense; 31; 10; 11-2012; 1489-1495
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