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dc.contributor.author
Gallo, Cristian Andrés
dc.contributor.author
Carballido, Jessica Andrea
dc.contributor.author
Ponzoni, Ignacio
dc.date.available
2018-11-21T18:59:12Z
dc.date.issued
2009-07
dc.identifier.citation
Gallo, Cristian Andrés; Carballido, Jessica Andrea; Ponzoni, Ignacio; BiHEA: A hybrid evolutionary approach for microarray biclustering; Springer; Lecture Notes in Computer Science; 5676 LNBI; 7-2009; 36-47
dc.identifier.isbn
978-3-642-03223-3
dc.identifier.issn
0302-9743
dc.identifier.uri
http://hdl.handle.net/11336/64882
dc.description.abstract
In this paper a new hybrid approach that integrates an evolutionary algorithm with local search for microarray biclustering is presented. The novelty of this proposal is constituted by the incorporation of two mechanisms: the first one avoids loss of good solutions through generations and overcomes the high degree of overlap in the final population; and the other one preserves an adequate level of genotypic diversity. The performance of the memetic strategy was compared with the results of several salient biclustering algorithms over synthetic data with different overlap degrees and noise levels. In this regard, our proposal achieves results that outperform the ones obtained by the referential methods. Finally, a study on real data was performed in order to demonstrate the biological relevance of the results of our approach. © 2009 Springer Berlin Heidelberg.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Springer
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Biclustering
dc.subject
Evolutionary Algorithms
dc.subject
Gene Expression Data
dc.subject.classification
Ciencias de la Computación
dc.subject.classification
Ciencias de la Computación e Información
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
BiHEA: A hybrid evolutionary approach for microarray biclustering
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-10-12T14:48:23Z
dc.journal.volume
5676 LNBI
dc.journal.pagination
36-47
dc.journal.pais
Alemania
dc.journal.ciudad
Berlin
dc.description.fil
Fil: Gallo, Cristian Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Sur; Argentina
dc.description.fil
Fil: Carballido, Jessica Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Sur; Argentina
dc.description.fil
Fil: Ponzoni, Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universidad Nacional del Sur; Argentina
dc.journal.title
Lecture Notes in Computer Science
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1007/978-3-642-03223-3_4
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/chapter/10.1007/978-3-642-03223-3_4


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