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dc.contributor.author
Osorio, Johan S.
dc.contributor.author
Vailati Riboni, Mario
dc.contributor.author
Palladino, Rafael Alejandro
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dc.contributor.author
Luo, Jun
dc.contributor.author
Loor, Juan J.
dc.date.available
2018-09-11T19:59:46Z
dc.date.issued
2017-09
dc.identifier.citation
Osorio, Johan S.; Vailati Riboni, Mario; Palladino, Rafael Alejandro; Luo, Jun; Loor, Juan J.; Application of nutrigenomics in small ruminants: Lactation, growth, and beyond; Elsevier Science; Journal of Small Ruminant Research; 154; 9-2017; 29-44
dc.identifier.issn
0921-4488
dc.identifier.uri
http://hdl.handle.net/11336/59166
dc.description.abstract
Ruminants have a very special niche in the animal kingdom, and are the most important livestock species providing milk, meat, and wool for humans from consumption of highly-fibrous feedstuffs. Cattle, goat and sheep have been widely-used for years as models to study ruminal fermentation and the mechanisms whereby tissues utilize nutrients for milk synthesis, growth, wool accretion, and reproduction. The advent of high-throughput technologies to study an animal's genome, proteome, and metabolome (i.e., “omics” tools) offered ruminant scientists the opportunity to study multiple levels of biological information to better understand the whole animal response to nutrition, environment, physiological state, and their interactions. The omics revolution gave rise to the field of nutrigenomics, i.e. the study of the genome-wide influences of nutrition through alteration in mRNA, protein, and metabolite expression or abundance. This field of research is relatively new in ruminants, and particularly sheep and goats. Dietary compounds affect gene expression directly or indirectly via interactions with transcription factors including ligand-dependent nuclear receptors. New knowledge generated through the application of functional analyses of transcriptomic, proteomic, and metabolomic data sets in goat and sheep is discussed.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subject
Bioinformatics
dc.subject
Genomics
dc.subject
Lactation
dc.subject
Nutrition
dc.subject
Ruminant
dc.subject.classification
Otras Producción Animal y Lechería
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dc.subject.classification
Producción Animal y Lechería
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dc.subject.classification
CIENCIAS AGRÍCOLAS
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dc.title
Application of nutrigenomics in small ruminants: Lactation, growth, and beyond
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-09-11T14:51:39Z
dc.journal.volume
154
dc.journal.pagination
29-44
dc.journal.pais
Países Bajos
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dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Osorio, Johan S.. South Dakota State University; Estados Unidos
dc.description.fil
Fil: Vailati Riboni, Mario. University of Illinois at Urbana; Estados Unidos
dc.description.fil
Fil: Palladino, Rafael Alejandro. Universidad de Buenos Aires. Facultad de Agronomía; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Luo, Jun. Northwest A&F University; China
dc.description.fil
Fil: Loor, Juan J.. University of Illinois at Urbana; Estados Unidos
dc.journal.title
Journal of Small Ruminant Research
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0921448817301803
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.smallrumres.2017.06.021
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