Artículo
Truncatones A–D, benzo[j]fluoranthenes from Annulohypoxylon species (Xylariaceae, Ascomycota)
Fecha de publicación:
10/2016
Editorial:
Pergamon-Elsevier Science Ltd
Revista:
Tetrahedron
ISSN:
0040-4020
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
From stromata (fruiting bodies) of three xylariaceous fungi belonging to the genus Annulohypoxylon (A. leptascum, A. cf. truncatum and an unidentified Annulohypoxylon sp.), truncatone A (1), three unprecedented derivatives named truncatones B–D (2–4) besides the known 4,5,4′,5′-tetrahydroxy-1,1′-binaphthyl (BNT, 5), hypoxylonol C (6) and hypoxylonol F (7) were isolated. Planar structures of the new benzo[j]fluoranthene derivatives 2–4 were determined on the basis of NMR and HRESIMS data. While the relative configuration of 4 was demonstrated by ROESY NMR data and1H,1H coupling constants, absolute configurations of 1, 2, 4 were determined by CD spectroscopy. Compounds 1, 3 and 4 exhibited cytotoxicity against the mouse fibroblast cell line L929.
Palabras clave:
Annulohypoxylon
,
Benzo[J]Fluoranthene
,
Cd
,
Nmr
,
Xylareceae
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Identificadores
Colecciones
Articulos(CCT - NOA SUR)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - NOA SUR
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - NOA SUR
Citación
Sudarman, Enge; Kuhnert, Eric; Hyde, Kevi D.; Sir, Esteban Benjamin; Surup, Frank; et al.; Truncatones A–D, benzo[j]fluoranthenes from Annulohypoxylon species (Xylariaceae, Ascomycota); Pergamon-Elsevier Science Ltd; Tetrahedron; 72; 41; 10-2016; 6450-6454
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