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dc.contributor.author
Gallo, Loreana Carolina
dc.contributor.author
Llabot, Juan Manuel
dc.contributor.author
Allemandi, Daniel Alberto
dc.contributor.author
Bucala, Veronica
dc.contributor.author
Piña, Juliana
dc.date.available
2018-08-17T17:20:06Z
dc.date.issued
2011-03
dc.identifier.citation
Gallo, Loreana Carolina; Llabot, Juan Manuel; Allemandi, Daniel Alberto; Bucala, Veronica; Piña, Juliana; Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties; Elsevier Science Sa; Powder Technology; 208; 1; 3-2011; 205-214
dc.identifier.issn
0032-5910
dc.identifier.uri
http://hdl.handle.net/11336/56195
dc.description.abstract
The aim of this work was to study Rhamnus purshiana (Cáscara sagrada) extract spray-drying in order to obtain powders with good rheological properties for direct compression (DC) and stability attributes. The experiments were carried out in a Büchi B-290 Mini Spray Dryer using colloidal silicon dioxide as carrier agent. A 25-1 fractional factorial statistical design was used to find adequate spray-drying operating conditions to produce Cáscara sagrada powders with good flow, good compactability properties, high process yield, low moisture content, low hygroscopicity, and caking tendency. Morphology, size, structural and thermal properties of the particles were also evaluated. The operating variables studied were air inlet temperature, atomization air flow rate, pump feed rate, aspiration capacity, and feed solids concentration. The 25-1 factorial experimental design used was a good strategy to establish spray-drying operating conditions to produce Cáscara sagrada extract powders with good properties for direct compression and high process yields. Colloidal silicon dioxide was an effective drying adjuvant. Its use in relatively high concentrations together with low atomization air flow rates improved powder flowability, increased the product's glass transition temperature, and decreased its moisture content and hygroscopicity.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science Sa
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subject
Cáscara Sagrada
dc.subject
Direct Compression
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Dry Plant Extract
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Factorial Design
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Rhamnus Purshiana
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Spray-Drying
dc.subject.classification
Recubrimientos y Películas
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Ingeniería de los Materiales
dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
dc.title
Influence of spray-drying operating conditions on Rhamnus purshiana (Cáscara sagrada) extract powder physical properties
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-07-11T13:59:33Z
dc.journal.volume
208
dc.journal.number
1
dc.journal.pagination
205-214
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Gallo, Loreana Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
dc.description.fil
Fil: Llabot, Juan Manuel. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Allemandi, Daniel Alberto. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Bucala, Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
dc.description.fil
Fil: Piña, Juliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
dc.journal.title
Powder Technology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.powtec.2010.12.021
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0032591010006522


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