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dc.contributor.author
Salerno, A.
dc.contributor.author
Fanovich, Maria Alejandra
dc.contributor.author
Domingo Pascual, C.
dc.date.available
2016-02-29T14:10:42Z
dc.date.issued
2014-10-22
dc.identifier.citation
Salerno, A.; Fanovich, Maria Alejandra; Domingo Pascual, C.; The effect of ethyl-lactate and ethyl-acetate plasticizers on PCL and PCL-HA composites foamed with supercritical CO2; Elsevier Science; Journal of Supercritical Fluids; 95; 22-10-2014; 394-406
dc.identifier.issn
0896-8446
dc.identifier.uri
http://hdl.handle.net/11336/4497
dc.description.abstract
The present study reports foaming of polycaprolactone (PCL) and PCL nano- and micro-composites with dispersed hydroxyapatite (HA) particles by means of binary mixtures of supercritical CO2 (scCO2) and either ethyl lactate (EL) or ethyl acetate (EA) as plasticizer. The effect of the size and concentration of HA particles, as well as the effects of the plasticizer type and the incorporation route were investigated aiming to fabricate porous scaffolds with uniform morphology and controlled pore size distribution. For this purpose, foaming experiments were carried out by selecting two operating temperatures, 40 and 45 °C, and two soaking times, 1 and 17 h. Furthermore, a double step of depressurization was used to promote the development of a double-scale pore size structure in porous scaffolds useful for tissue engineering. The results of this study indicated that supercritical foaming of PCL and PCL-HA composites is enhanced when the selected operating temperature and time are 45 °C and 17 h, respectively. Furthermore, although both EL and EA plasticizers enhanced the low temperature foaming of the materials, we demonstrated that the route of incorporation of the plasticizer is a critical aspect for enhancing composite foaming and scaffold fabrication. From this point of view, the best results were achieved when EA was pre-mixed with the polymeric powder for preparing a dough for the foaming process.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subject
CO2
dc.subject
FOAMING
dc.subject
HYDROXYAPATITE
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PLASTICIZER
dc.subject
POLYCAPROLACTONE
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SCAFFOLD
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SUPERCRITICAL
dc.subject.classification
Compuestos
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Ingeniería de los Materiales
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INGENIERÍAS Y TECNOLOGÍAS
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Físico-Química, Ciencia de los Polímeros, Electroquímica
dc.subject.classification
Ciencias Químicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
The effect of ethyl-lactate and ethyl-acetate plasticizers on PCL and PCL-HA composites foamed with supercritical CO2
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2016-03-30 10:35:44.97925-03
dc.journal.volume
95
dc.journal.pagination
394-406
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Salerno, A.. Institut de Ciència de Materials de Barcelona; España
dc.description.fil
Fil: Fanovich, Maria Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingeniería; Argentina
dc.description.fil
Fil: Domingo Pascual, C.. Institut de Ciència de Materials de Barcelona; España
dc.journal.title
Journal of Supercritical Fluids
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.supflu.2014.10.007
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S089684461400343X
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