Artículo
Neuroprotection in Hypoxic-Ischemic Brain Injury Targeting Glial Cells
Herrera, María Inés
; Mucci, Sofia; Barreto, George E; Kolliker Frers, Rodolfo Alberto
; Capani, Francisco
Fecha de publicación:
10/2017
Editorial:
Bentham Science Publishers
Revista:
Current Pharmaceutical Design
ISSN:
1381-6128
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Brain injury constitutes a disabling health condition of several etiologies. One of the major causes of brain injury is hypoxia-ischemia. Until recently, pharmacological treatments were solely focused on neurons. In the last decades, glial cells started to be considered as alternative targets for neuroprotection. Novel treatments for hypoxia-ischemia intend to modulate reactive forms of glial cells, and/or potentiate their recovery response. In this review, we summarize these neuroprotective strategies in hypoxia-ischemia and discuss their mechanisms of action.
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Articulos(ININCA)
Articulos de INST.DE INVEST.CARDIOLOGICAS (I)
Articulos de INST.DE INVEST.CARDIOLOGICAS (I)
Citación
Herrera, María Inés; Mucci, Sofia; Barreto, George E; Kolliker Frers, Rodolfo Alberto; Capani, Francisco; Neuroprotection in Hypoxic-Ischemic Brain Injury Targeting Glial Cells; Bentham Science Publishers; Current Pharmaceutical Design; 23; 26; 10-2017; 1-8
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