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dc.contributor.author Santamaria Garcia, Hernando
dc.contributor.author Báez Buitrago, Sandra Jimena
dc.contributor.author Reyes, Pablo
dc.contributor.author Santamaría García, José A.
dc.contributor.author Santacruz Escudero, José M.
dc.contributor.author Matallana, Diana
dc.contributor.author Arévalo, Analía
dc.contributor.author Sigman, Mariano
dc.contributor.author García, Adolfo Martín
dc.contributor.author Ibáñez Barassi, Agustín Mariano
dc.date.available 2018-04-09T20:32:44Z
dc.date.issued 2017-12
dc.identifier.citation Santamaria Garcia, Hernando; Báez Buitrago, Sandra Jimena; Reyes, Pablo; Santamaría García, José A.; Santacruz Escudero, José M.; et al.; A lesion model of envy and Schadenfreude: legal, deservingness and moral dimensions as revealed by neurodegeneration; Oxford University Press; Brain; 140; 12; 12-2017; 3357-3377
dc.identifier.issn 0006-8950
dc.identifier.uri http://hdl.handle.net/11336/41424
dc.description.abstract The study of moral emotions (i.e. Schadenfreude and envy) is critical to understand the ecological complexity of everyday interactions between cognitive, affective, and social cognition processes. Most previous studies in this area have used correlational imaging techniques and framed Schadenfreude and envy as unified and monolithic emotional domains. Here, we profit from a relevant neurodegeneration model to disentangle the brain regions engaged in three dimensions of Schadenfreude and envy: deservingness, morality, and legality. We tested a group of patients with behavioural variant frontotemporal dementia (bvFTD), patients with Alzheimer’s disease, as a contrastive neurodegeneration model, and healthy controls on a novel task highlighting each of these dimensions in scenarios eliciting Schadenfreude and envy. Compared with the Alzheimer’s disease and control groups, patients with bvFTD obtained significantly higher scores on all dimensions for both emotions. Correlational analyses revealed an association between envy and Schadenfreude scores and greater deficits in social cognition, inhibitory control, and behaviour disturbances in bvFTD patients. Brain anatomy findings (restricted to bvFTD and controls) confirmed the partially dissociable nature of the moral emotions’ experiences and highlighted the importance of socio-moral brain areas in processing those emotions. In all subjects, an association emerged between Schadenfreude and the ventral striatum, and between envy and the anterior cingulate cortex. In addition, the results supported an association between scores for moral and legal transgression and the morphology of areas implicated in emotional appraisal, including the amygdala and the parahippocampus. By contrast, bvFTD patients exhibited a negative association between increased Schadenfreude and envy across dimensions and critical regions supporting social-value rewards and social-moral processes (dorsolateral prefrontal cortex, angular gyrus and precuneus). Together, this study provides lesion-based evidence for the multidimensional nature of the emotional experiences of envy and Schadenfreude. Our results offer new insights into the mechanisms subsuming complex emotions and moral cognition in neurodegeneration. Moreover, this study presents the exacerbation of envy and Schadenfreude as a new potential hallmark of bvFTD that could impact in diagnosis and progression.
dc.format application/pdf
dc.language.iso eng
dc.publisher Oxford University Press
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject Dementia
dc.subject Social cognition
dc.subject Brain atrophy
dc.subject Frontotemporal dementia
dc.subject.classification Neurociencias
dc.subject.classification Medicina Básica
dc.subject.classification CIENCIAS MÉDICAS Y DE LA SALUD
dc.title A lesion model of envy and Schadenfreude: legal, deservingness and moral dimensions as revealed by neurodegeneration
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2018-04-09T15:06:14Z
dc.journal.volume 140
dc.journal.number 12
dc.journal.pagination 3357-3377
dc.journal.pais Reino Unido
dc.journal.ciudad Oxford
dc.description.fil Fil: Santamaria Garcia, Hernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Intellectus-Hospital Universitario San Ignacio; Colombia. Pontificia Universidad Javeriana; Colombia
dc.description.fil Fil: Báez Buitrago, Sandra Jimena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad de Los Andes; Colombia. Grupo de Investigación en Cerebro y Cognición Social; Colombia
dc.description.fil Fil: Reyes, Pablo. Intellectus-Hospital Universitario San Ignacio; Colombia. Pontificia Universidad Javeriana; Colombia
dc.description.fil Fil: Santamaría García, José A.. Universidad de Los Andes; Colombia
dc.description.fil Fil: Santacruz Escudero, José M.. Intellectus-Hospital Universitario San Ignacio; Colombia. Pontificia Universidad Javeriana; Colombia. Universitat Autònoma de Barcelona; España
dc.description.fil Fil: Matallana, Diana. Pontificia Universidad Javeriana; Colombia. Intellectus-Hospital Universitario San Ignacio; Colombia
dc.description.fil Fil: Arévalo, Analía. Universidade de Sao Paulo; Brasil
dc.description.fil Fil: Sigman, Mariano. Universidad Torcuato di Tella; Argentina
dc.description.fil Fil: García, Adolfo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Cuyo; Argentina
dc.description.fil Fil: Ibáñez Barassi, Agustín Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Autónoma del Caribe; Colombia. Universidad Adolfo Ibañez; Chile. Universidad Autónoma del Caribe; Australia
dc.journal.title Brain
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/brain/article/140/12/3357/4588353
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1093/brain/awx269
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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)