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dc.contributor.author
Fara, María Agustina  
dc.contributor.author
Hernandez Hernandez, Oswaldo  
dc.contributor.author
Montilla, Antonia  
dc.contributor.author
Zarate, Gabriela del Valle  
dc.date.available
2024-04-17T13:34:11Z  
dc.date.issued
2023-02  
dc.identifier.citation
Fara, María Agustina; Hernandez Hernandez, Oswaldo; Montilla, Antonia; Zarate, Gabriela del Valle; In vitro digestibility of oligosaccharides synthesized by dairy propionibacteria β-galactosidase from lactose, lactulose and lactitol; Elsevier; Food Bioscience; 51; 2-2023; 1-7  
dc.identifier.issn
2212-4292  
dc.identifier.uri
http://hdl.handle.net/11336/233276  
dc.description.abstract
Prebiotics synthesized by probiotic genera are of interest due to their specific selectivity. However, modifications of their composition and concentrations by digestion may affect their properties and effects in the host. In the present study we assessed small intestinal digestibility of oligosaccharides synthesized by Acidipropionibacterium acidipropionici LET120-β-gal (β-galactosidase) from lactose (LET120-GOS), lactulose (LET120-OsLu) and lactitol (LET120-LOS) by incubating them with brush border membrane vesicles (BBMV) from pig and a rat small intestinal extract (RSIE) as in vitro models of mammalian mucosa. Both BBMVs and RSIE partially degraded the potential prebiotic oligosaccharides synthesized by dairy propionibacteria and hydrolysis was influenced by the structure and composition of the oligosaccharides. The highest degradation was observed for LET120–GOS, with 46.8% and 58.1% of hydrolysis after 5 h of digestion with BBMV and RSIE, respectively. On the contrary, LET120-OsLu and LET120-LOS showed higher resistance to intestinal degradation. β(1 → 6) linked products showed higher resistance to mammalian digestive enzymes compared to β(1 → 4) and β(1 → 3) linked oligosaccharides. Results emphasize the need of quantifying prebiotics that would reach the colon to anticipate their impact on health and the dose needed to exert that effect.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
BRUSH BORDER MEMBRANE VESICLES (BBMV) FROM PIG  
dc.subject
OLIGOSACCHARIDES  
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PROPIONIBACTERIA  
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RAT SMALL INTESTINAL EXTRACT (RSIE)  
dc.subject.classification
Biología Celular, Microbiología  
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Ciencias Biológicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
In vitro digestibility of oligosaccharides synthesized by dairy propionibacteria β-galactosidase from lactose, lactulose and lactitol  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2024-04-17T13:08:27Z  
dc.identifier.eissn
2212-4306  
dc.journal.volume
51  
dc.journal.pagination
1-7  
dc.journal.pais
Países Bajos  
dc.description.fil
Fil: Fara, María Agustina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina  
dc.description.fil
Fil: Hernandez Hernandez, Oswaldo. Consejo Superior de Investigaciones Científicas; España  
dc.description.fil
Fil: Montilla, Antonia. Consejo Superior de Investigaciones Científicas; España  
dc.description.fil
Fil: Zarate, Gabriela del Valle. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina  
dc.journal.title
Food Bioscience  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.fbio.2023.102362