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dc.contributor.author
Facciuto, Marcelo
dc.contributor.author
Contreras Saldivar, Alan
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Singh, Manoj K.
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Rocca, Juan Pablo
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Taouli, Bachir
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Oyfe, Irina
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LaPointe Rudow, Dianne
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Gondolesi, Gabriel Eduardo
dc.contributor.author
Schiano, Thomas
dc.contributor.author
Kim Schluger, Leona
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Schwartz, Myron E.
dc.contributor.author
Miller, Charles M.
dc.contributor.author
Florman, Sander
dc.date.available
2017-08-23T20:00:09Z
dc.date.issued
2013-02
dc.identifier.citation
Facciuto, Marcelo; Contreras Saldivar, Alan; Singh, Manoj K.; Rocca, Juan Pablo; Taouli, Bachir; et al.; Right hepatectomy for living donation: Role of remnant liver volume in predicting hepatic dysfunction and complications; Elsevier; Surgery; 153; 5; 2-2013; 619-626
dc.identifier.issn
0039-6060
dc.identifier.uri
http://hdl.handle.net/11336/22893
dc.description.abstract
BACKGROUND: Extensive attention has been placed on remnant liver volume (RLV) above other factors to ensure donor safety. METHODS: We performed a retrospective review of 137 right hepatectomies in live donors between June 1999 and November 2010. RESULTS: Median right lobe volume was 1,029 cm(3), which correlated with its actual weight (r = 0.63, P < .01); median RLV was 548 cm(3). Of the donors, 32 (24%) developed postoperative hepatic dysfunction (bilirubin >3 mg/dL or prothrombin time >18 s on postoperative day 4). RLV did not predict postoperative hepatic dysfunction (P = .9), but it was associated with peak international normalized ratio (INR) (P = .04). Donor age and male gender were predictors of increased bilirubin at postoperative day 4 (age, P = .03; gender, P = .02). Of the donors, 45 (33%) experienced complications, and 24 donors had RLVs <30%; 42% experienced complications compared to 31% of donors whose RLVs were greater than 30% (P = .3). Cell-saver utilization and aspartate-aminotransferase (AST) levels (OR = 3) were associated with complications. Volumetric assessment can predict RLV accurately. CONCLUSION: Although no demonstrable association between RLV <30% and complications was found, an RLV of 30% should remain the threshold for donor safety. Age and gender should be balanced in donors with a near threshold RLV of 30%. Surgical complexity, suggested by the need for intraoperative autoinfusion of blood and postoperative levels of AST, remained the independent predictor of complications.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Liver Trnasplant
dc.subject
Right Love
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Living Donor
dc.subject
Volume
dc.subject.classification
Reumatología
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Medicina Clínica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Right hepatectomy for living donation: Role of remnant liver volume in predicting hepatic dysfunction and complications
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-08-22T21:24:22Z
dc.journal.volume
153
dc.journal.number
5
dc.journal.pagination
619-626
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Maryland Heights
dc.description.fil
Fil: Facciuto, Marcelo. Mount Sinai Medical Center; Estados Unidos
dc.description.fil
Fil: Contreras Saldivar, Alan. Mount Sinai Medical Center; Estados Unidos
dc.description.fil
Fil: Singh, Manoj K.. Mount Sinai Medical Center; Estados Unidos
dc.description.fil
Fil: Rocca, Juan Pablo. Mount Sinai Medical Center; Estados Unidos
dc.description.fil
Fil: Taouli, Bachir. Mount Sinai Medical Center; Estados Unidos
dc.description.fil
Fil: Oyfe, Irina. Columbia University; Estados Unidos
dc.description.fil
Fil: LaPointe Rudow, Dianne. Mount Sinai Medical Center; Estados Unidos
dc.description.fil
Fil: Gondolesi, Gabriel Eduardo. Fundación Favaloro; Argentina. Universidad Favaloro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Schiano, Thomas. Mount Sinai Medical Center; Estados Unidos
dc.description.fil
Fil: Kim Schluger, Leona. Mount Sinai Medical Center; Estados Unidos
dc.description.fil
Fil: Schwartz, Myron E.. Mount Sinai Medical Center; Estados Unidos
dc.description.fil
Fil: Miller, Charles M.. Cleveland Clinic. Digestive Disease Institute. Department of Hepato-Pancreato-Biliary and Transplant Surgery ; Estados Unidos
dc.description.fil
Fil: Florman, Sander. Mount Sinai Medical Center; Estados Unidos
dc.journal.title
Surgery
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0039606012007337
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.surg.2012.11.020


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