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dc.contributor.author Facciuto, Marcelo
dc.contributor.author Contreras Saldivar, Alan
dc.contributor.author Singh, Manoj K.
dc.contributor.author Rocca, Juan Pablo
dc.contributor.author Taouli, Bachir
dc.contributor.author Oyfe, Irina
dc.contributor.author LaPointe Rudow, Dianne
dc.contributor.author Gondolesi, Gabriel Eduardo
dc.contributor.author Schiano, Thomas
dc.contributor.author Kim Schluger, Leona
dc.contributor.author Schwartz, Myron E.
dc.contributor.author Miller, Charles M.
dc.contributor.author Florman, Sander
dc.date.available 2017-08-23T20:00:09Z
dc.date.issued 2013-02
dc.identifier.citation Facciuto, Marcelo; Contreras Saldivar, Alan; Singh, Manoj K.; Rocca, Juan Pablo; Taouli, Bachir; et al.; Right hepatectomy for living donation: Role of remnant liver volume in predicting hepatic dysfunction and complications; Elsevier; Surgery; 153; 5; 2-2013; 619-626
dc.identifier.issn 0039-6060
dc.identifier.uri http://hdl.handle.net/11336/22893
dc.description.abstract BACKGROUND: Extensive attention has been placed on remnant liver volume (RLV) above other factors to ensure donor safety. METHODS: We performed a retrospective review of 137 right hepatectomies in live donors between June 1999 and November 2010. RESULTS: Median right lobe volume was 1,029 cm(3), which correlated with its actual weight (r = 0.63, P < .01); median RLV was 548 cm(3). Of the donors, 32 (24%) developed postoperative hepatic dysfunction (bilirubin >3 mg/dL or prothrombin time >18 s on postoperative day 4). RLV did not predict postoperative hepatic dysfunction (P = .9), but it was associated with peak international normalized ratio (INR) (P = .04). Donor age and male gender were predictors of increased bilirubin at postoperative day 4 (age, P = .03; gender, P = .02). Of the donors, 45 (33%) experienced complications, and 24 donors had RLVs <30%; 42% experienced complications compared to 31% of donors whose RLVs were greater than 30% (P = .3). Cell-saver utilization and aspartate-aminotransferase (AST) levels (OR = 3) were associated with complications. Volumetric assessment can predict RLV accurately. CONCLUSION: Although no demonstrable association between RLV <30% and complications was found, an RLV of 30% should remain the threshold for donor safety. Age and gender should be balanced in donors with a near threshold RLV of 30%. Surgical complexity, suggested by the need for intraoperative autoinfusion of blood and postoperative levels of AST, remained the independent predictor of complications.
dc.format application/pdf
dc.language.iso eng
dc.publisher Elsevier
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject Liver trnasplant
dc.subject Right love
dc.subject Living donor
dc.subject Volume
dc.subject.classification Reumatología
dc.subject.classification Medicina Clínica
dc.subject.classification CIENCIAS MÉDICAS Y DE LA SALUD
dc.title Right hepatectomy for living donation: Role of remnant liver volume in predicting hepatic dysfunction and complications
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2017-08-22T21:24:22Z
dc.journal.volume 153
dc.journal.number 5
dc.journal.pagination 619-626
dc.journal.pais Estados Unidos
dc.journal.ciudad Maryland Heights
dc.description.fil Fil: Facciuto, Marcelo. Mount Sinai Medical Center; Estados Unidos
dc.description.fil Fil: Contreras Saldivar, Alan. Mount Sinai Medical Center; Estados Unidos
dc.description.fil Fil: Singh, Manoj K.. Mount Sinai Medical Center; Estados Unidos
dc.description.fil Fil: Rocca, Juan Pablo. Mount Sinai Medical Center; Estados Unidos
dc.description.fil Fil: Taouli, Bachir. Mount Sinai Medical Center; Estados Unidos
dc.description.fil Fil: Oyfe, Irina. Columbia University; Estados Unidos
dc.description.fil Fil: LaPointe Rudow, Dianne. Mount Sinai Medical Center; Estados Unidos
dc.description.fil Fil: Gondolesi, Gabriel Eduardo. Fundación Favaloro; Argentina. Universidad Favaloro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil Fil: Schiano, Thomas. Mount Sinai Medical Center; Estados Unidos
dc.description.fil Fil: Kim Schluger, Leona. Mount Sinai Medical Center; Estados Unidos
dc.description.fil Fil: Schwartz, Myron E.. Mount Sinai Medical Center; Estados Unidos
dc.description.fil Fil: Miller, Charles M.. Cleveland Clinic. Digestive Disease Institute. Department of Hepato-Pancreato-Biliary and Transplant Surgery ; Estados Unidos
dc.description.fil Fil: Florman, Sander. Mount Sinai Medical Center; Estados Unidos
dc.journal.title Surgery
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0039606012007337
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.surg.2012.11.020


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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)