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Gerez Miranda, Rocío del Carmen  
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Marandino, Ana  
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Tomas, Gonzalo  
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Olivera, Valeria  
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Pinto, Blanca Silvina  
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Craig, María Isabel  
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Techera, Claudia  
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Perez, Ruben  
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Vagnozzi, Ariel Eduardo  
dc.date.available
2023-01-19T14:09:47Z  
dc.date.issued
2021-08  
dc.identifier.citation
Gerez Miranda, Rocío del Carmen; Marandino, Ana; Tomas, Gonzalo; Olivera, Valeria; Pinto, Blanca Silvina; et al.; Evaluation of the Efficiency of Commercial Vaccines against Infectious Bronchitis Virus (IBV) Belonging to the GI-16 Lineage Isolated in an Argentinean Outbreak; American Association of Avian Pathologists; Avian Diseases; 65; 3; 8-2021; 456-462  
dc.identifier.issn
0005-2086  
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http://hdl.handle.net/11336/185012  
dc.description.abstract
In this study we evaluated the effectiveness of adding serotype 793B vaccine to an immunization program in order to control the infectious bronchitis virus (IBV) GI-16 lineage. Therefore, two different experiments were performed. First, a virus cross-neutralization test was carried out, which indicated that neither the Massachusetts (Mass) nor 793B serotypes are antigenically related to the field isolate A13 (GI-16). We also performed a challenge trial to evaluate if the Mass/793B combination is more efficient than Mass/Connecticut (Conn) to protect chickens against the Argentinian variant A13. Thus, 40 chickens were organized in four groups. Chickens in Group A were vaccinated at 1 day of age with Mass serotype and then at 14 days old with Mass plus Conn serotypes. Chickens in Group B received Mass and 793B serotypes at 1 and 14 days old, respectively. Groups C and D remained unvaccinated. At 28 days of age, Groups A, B, and C were challenged with the A13 isolate, while Group D remained as the negative control. The statistical analysis of the ciliostasis evaluation, performed at 7 days postchallenge (dpch), indicated that the difference between Mass/793B and Mass/Conn was not significant (p > 0.05). However, the comparison against the negative control showed that only Group A was significantly different, suggesting a slightly better performance on blocking ciliostasis for the Mass/793B combination. On the other hand, no significant differences were observed in the viral load, quantified by reverse-transcription quantitative real-time PCR (RT-qPCR) in tracheal swabs and kidneys (at 3 and 7 dpch, respectively) between vaccinated groups. Furthermore, some amounts of the viral genome were found in both vaccinated groups that could indicate that neither the Mass/793B nor the Mass/Conn combinations totally inhibited the viral replication. Such viral replication in vaccinated chickens should seriously be taken into consideration because it could promote the selection of new variants in the future.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
American Association of Avian Pathologists  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
CHALLENGE TRIAL  
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CILIOSTASIS  
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INFECTIOUS BRONCHITIS VIRUS  
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PARTIAL PROTECTION  
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REAL TIME RT-PCR  
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SEROTYPE COMBINATION  
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VACCINE EFFICIENCY  
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VIRAL LOAD QUANTITATION  
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VIRUS CROSS-NEUTRALIZATION  
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Ciencias Veterinarias  
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Ciencias Veterinarias  
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CIENCIAS AGRÍCOLAS  
dc.title
Evaluation of the Efficiency of Commercial Vaccines against Infectious Bronchitis Virus (IBV) Belonging to the GI-16 Lineage Isolated in an Argentinean Outbreak  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
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info:eu-repo/semantics/publishedVersion  
dc.date.updated
2022-09-23T10:06:53Z  
dc.journal.volume
65  
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3  
dc.journal.pagination
456-462  
dc.journal.pais
Estados Unidos  
dc.description.fil
Fil: Gerez Miranda, Rocío del Carmen. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología e Innovaciones Tecnológicas. - Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Virología e Innovaciones Tecnológicas; Argentina  
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Fil: Marandino, Ana. Universidad de la Republica; Uruguay  
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Fil: Tomas, Gonzalo. Universidad de la República; Uruguay  
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Fil: Olivera, Valeria. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina  
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Fil: Pinto, Blanca Silvina. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina  
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Fil: Craig, María Isabel. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina  
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Fil: Techera, Claudia. Universidad de la República; Uruguay  
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Fil: Perez, Ruben. Universidad de la Republica; Uruguay  
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Fil: Vagnozzi, Ariel Eduardo. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina  
dc.journal.title
Avian Diseases  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://bioone.org/journals/avian-diseases/volume-65/issue-3/0005-2086-65.3.456/Evaluation-of-the-Efficiency-of-Commercial-Vaccines-Against-Infectious-Bronchitis/10.1637/0005-2086-65.3.456.short  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1637/0005-2086-65.3.456