Capítulo de Libro
Alcohol toxicity: the role of oxidative stress
Título del libro: Toxicology: Oxidative Stress and Dietary Antioxidants
Fecha de publicación:
2021
Editorial:
Academic Press
ISBN:
9780128190920
Idioma:
Inglés
Clasificación temática:
Resumen
Ethanol, the major component of alcoholic beverages, is one of the most consumed substances in the world causing millions of deaths due to its harmful use. Oxidative stress and the consequent disruption of redox signalling can lead to cell damage. Free radical generation has been proposed as one of the main mechanisms responsible of EtOH-induced multi-organ damage. Indeed, alcohol abuse can trigger several mechanisms of toxicity in different tissues including liver, kidney, ear, and cardiovascular and nervous systems. Here, we show scientific evidences about most important effects of chronic and acute alcohol abuse discussing the role of oxidative stress in alcohol toxicity in different tissues and organs. Although biochemical pathways underlying EtOH-induced disease are not completely understood, it is generally accepted that free radical overproduction could trigger and aggravate alcohol-related diseases.
Palabras clave:
DRUG TOXICITY
,
ALCOHOL
,
FREE RADICALS
,
OXIDATIVE STRESS
Archivos asociados
Licencia
Identificadores
Colecciones
Capítulos de libros(IBIMOL)
Capítulos de libros de INSTITUTO DE BIOQUIMICA Y MEDICINA MOLECULAR
Capítulos de libros de INSTITUTO DE BIOQUIMICA Y MEDICINA MOLECULAR
Citación
Karadayian, Analia Graciela; Bustamante, Juanita; Lores Arnaiz, Silvia; Alcohol toxicity: the role of oxidative stress; Academic Press; 2021; 225-232
Compartir