Artículo
Strontium titanate (SrTiO3) mesoporous coatings for enhanced strontium delivery and osseointegration on bone implants
Escobar, Ane; Muzzio, Nicolás Eduardo
; Angelome, Paula Cecilia
; Bordoni, Andrea Veronica
; Martínez, Angel; Bindini, Elisa; Coy, Emerson; Andreozzi, Patrizia; Grzelczak, Marek; Moya, Sergio E.
Fecha de publicación:
07/2019
Editorial:
Wiley VCH Verlag
Revista:
Advanced Engineering Materials (print)
ISSN:
1438-1656
e-ISSN:
1527-2648
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The incorporation of strontium (Sr) in titania enhances surface bioactivity and has a positive effect on pre-osteoblastic cell attachment, proliferation, and differentiation. Strontium titanate mesoporous films (SrTiMFs) with 30% pore volume and a 20% Sr molar content have been prepared by the evaporation induced self-assembly method. SrTiMFs display a large internal surface area available for exchange of Sr, which is released in cell media up to 44% within the first 8 h. SrTiMFs improve attachment of MC3T3-E1 pre-osteoblastic cells, which show larger filopodia and more elongated features than cells attached to plain mesoporous titania films (MTFs). SrTiMFs also display improved cell proliferation and differentiation rates indicating that overall Sr incorporation into mesoporous titania coatings can lead to enhanced osseointegration during the early stages of bone tissue formation.
Palabras clave:
MESOPOROUS THIN FILMS
,
OSSEOINTEGRATION
,
PRE-OSTEOBLASTS
,
STRONTIUM TITANATE
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos (UE-INN - NODO CONSTITUYENTES)
Articulos de UNIDAD EJECUTORA INSTITUTO DE NANOCIENCIA Y NANOTECNOLOGIA - NODO CONSTITUYENTES
Articulos de UNIDAD EJECUTORA INSTITUTO DE NANOCIENCIA Y NANOTECNOLOGIA - NODO CONSTITUYENTES
Articulos(IFIBA)
Articulos de INST.DE FISICA DE BUENOS AIRES
Articulos de INST.DE FISICA DE BUENOS AIRES
Citación
Escobar, Ane; Muzzio, Nicolás Eduardo; Angelome, Paula Cecilia; Bordoni, Andrea Veronica; Martínez, Angel; et al.; Strontium titanate (SrTiO3) mesoporous coatings for enhanced strontium delivery and osseointegration on bone implants; Wiley VCH Verlag; Advanced Engineering Materials (print); 21; 7; 7-2019; 1-8
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