Artículo
Ferroptosis in plants: triggers, proposed mechanisms and the role of iron in modulating cell death
Distefano, Ayelen Mariana
; Lopez, Gabriel Alejandro; Setzes, Nicolás
; Marchetti, Maria Fernanda
; Cainzos Gelabert, Maximiliano Guillermo
; Cascallares, María Milagros
; Zabaleta, Eduardo Julian
; Pagnussat, Gabriela Carolina
Fecha de publicación:
09/2020
Editorial:
Oxford University Press
Revista:
Journal of Experimental Botany
ISSN:
0022-0957
e-ISSN:
1460-2431
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Regulated cell death plays key roles during essential processes along the plant life cycle. It takes part of specific developmental programs and maintains the organism homeostasis in response to unfavorable environments. Ferroptosis is a recently discovered iron-dependent cell death pathway characterized by the accumulation of lipid reactive oxygen species. Ferroptosis in plants shares all the main hallmarks described for ferroptosis in other systems. Those specific features include biochemical and morphological signatures that seem conserved among species. However, plant cells have specific metabolic pathways and a high degree of metabolic compartmentalization. Together with their particular morphology, these features add more complexity to the plant ferroptosis pathway. In this review, we summarize the most recent advances in elucidating the roles of ferroptosis in plants, focusing on specific triggers, main players and underlying pathways.
Palabras clave:
FERROPTOSIS
,
CELL DEATH
,
ARABIDOPSIS
,
IRON METABOLISM
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Articulos(IIB)
Articulos de INSTITUTO DE INVESTIGACIONES BIOLOGICAS
Articulos de INSTITUTO DE INVESTIGACIONES BIOLOGICAS
Citación
Distefano, Ayelen Mariana; Lopez, Gabriel Alejandro; Setzes, Nicolás; Marchetti, Maria Fernanda; Cainzos Gelabert, Maximiliano Guillermo; et al.; Ferroptosis in plants: triggers, proposed mechanisms and the role of iron in modulating cell death; Oxford University Press; Journal of Experimental Botany; 72; 6; 9-2020; 2125-2135
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