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dc.contributor.author
Condat, Carlos  
dc.contributor.author
Menchón, Silvia Adriana  
dc.date.available
2021-05-20T15:22:48Z  
dc.date.issued
2006-11  
dc.identifier.citation
Condat, Carlos; Menchón, Silvia Adriana; Ontogenetic growth of multicellular tumor spheroids; Elsevier Science; Physica A: Statistical Mechanics and its Applications; 371; 1; 11-2006; 76-79  
dc.identifier.issn
0378-4371  
dc.identifier.uri
http://hdl.handle.net/11336/132356  
dc.description.abstract
In ontogenetic growth models, the basal metabolic rate is usually assumed to depend on the individual mass following a power law. Here it is shown that, in the case of multicellular tumor spheroids, the emergence of a necrotic core invalidates this assumption. The implications of this result for spheroid growth are discussed, and a procedure to determine the growth parameters using macroscopic measurements is proposed.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier Science  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
CANCER  
dc.subject
DIFFUSION  
dc.subject
MULTICELLULAR TUMOR SPHEROID  
dc.subject
NECROSIS  
dc.subject
ONTOGENETIC GROWTH  
dc.subject.classification
Física de los Materiales Condensados  
dc.subject.classification
Ciencias Físicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Ontogenetic growth of multicellular tumor spheroids  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2021-04-23T16:51:53Z  
dc.journal.volume
371  
dc.journal.number
1  
dc.journal.pagination
76-79  
dc.journal.pais
Países Bajos  
dc.journal.ciudad
Amsterdam  
dc.description.fil
Fil: Condat, Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina  
dc.description.fil
Fil: Menchón, Silvia Adriana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina  
dc.journal.title
Physica A: Statistical Mechanics and its Applications  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.physa.2006.04.082  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0378437106005036  

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