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dc.contributor.author
Gorustovich Alonso, Alejandro Adrian  
dc.contributor.author
Nielsen, Forrest H.  
dc.date.available
2021-04-23T11:43:21Z  
dc.date.issued
2018-09-04  
dc.identifier.citation
Gorustovich Alonso, Alejandro Adrian; Nielsen, Forrest H.; Effects of Nutritional Deficiency of Boron on the Bones of the Appendicular Skeleton of Mice; Humana Press; Biological Trace Element Research; 188; 1; 4-9-2018; 221-229  
dc.identifier.issn
0163-4984  
dc.identifier.uri
http://hdl.handle.net/11336/130753  
dc.description.abstract
Scientific evidence has shown the nutritional importance of boron (B) in the remodeling and repair of cancellous bone tissue. However, the effects of the nutritional deficiency of B on the cortical bone tissue of the appendicular skeleton have not yet been described. Thus, a study was performed to histomorphometrically evaluate the density of osteocyte lacunae of cortical bone of mouse femora under conditions of nutritional deficiency of B and to analyze the effects of the deficiency on the biomechanical properties of mouse tibiae. Weaning, 21-day-old male Swiss mice were assigned to the following two groups: Controls (B+; n = 10) and Experimental (B-; n = 10). Control mice were fed a basal diet containing 3 mg B/Kg, whereas experimental mice were fed a B-deficient diet containing 0.07 mg B/Kg for 9 weeks. The histological and histomorphometric evaluations of the mice fed a B-deficient diet showed a decrease in the density of osteocyte lacunae in the femoral cortical bone tissue and the evaluation of biomechanical properties showed lower bone rigidity in the tibia.  
dc.description.abstract
. . . .  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Humana Press  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Boron  
dc.subject
Cortical bone  
dc.subject
Osteocyte lacunae  
dc.subject
Histomorphometry  
dc.subject
Biomechanical properties  
dc.subject.classification
Otras Ciencias de la Salud  
dc.subject.classification
Ciencias de la Salud  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Effects of Nutritional Deficiency of Boron on the Bones of the Appendicular Skeleton of Mice  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2020-11-18T20:50:51Z  
dc.identifier.eissn
1559-0720  
dc.journal.volume
188  
dc.journal.number
1  
dc.journal.pagination
221-229  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Nueva York  
dc.description.fil
Fil: Gorustovich Alonso, Alejandro Adrian. Universidad Católica de Salta; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Tecnologías y Ciencias de la Ingenieria "Hilario Fernandez Long". Grupo Vinculado al Intecin - Grupo Interdisciplinario en Materiales; Argentina  
dc.description.fil
Fil: Nielsen, Forrest H.. No especifíca;  
dc.journal.title
Biological Trace Element Research  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://link.springer.com/10.1007/s12011-018-1499-3  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s12011-018-1499-3