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dc.contributor.author
Diaz, Alberto Alejandro
dc.contributor.author
Zócalo, Yanina
dc.contributor.author
Bia, Daniel
dc.date.available
2020-12-02T13:06:38Z
dc.date.issued
2019-03
dc.identifier.citation
Diaz, Alberto Alejandro; Zócalo, Yanina; Bia, Daniel; Percentile curves for left ventricle structural, functional and haemodynamic parameters obtained in healthy children and adolescents from echocardiography-derived data; Springer; Journal of Echocardiography; 18; 1; 3-2019; 16-43
dc.identifier.issn
1349-0222
dc.identifier.uri
http://hdl.handle.net/11336/119556
dc.description.abstract
Background Transthoracic echocardiography is the most common non-invasive technique for the study of the left ventricle (LV) and the proximal aorta. Despite the clinical value, there is scarcity of data about reference intervals (RIs) and percentiles for thoracic aorta dimension and LV structural and functional parameters, obtained from population-based studies in children and adolescents. The aim was to generate RIs for LV, haemodynamic and thoracic aorta parameters obtained from transthoracic echocardiography in healthy children, adolescents and young adults from a South-American population. Methods One thousand ninety-five healthy subjects (5–24 years) were studied (M-mode, B-mode and Doppler echocardiography). Results RIs for LV structural (diameters, volumes and wall thickness) and functional (stroke volume, cardiac output, cardiac index, transmitral E and A fow waves velocities) parameters; systemic vascular resistance and aortic root diameter were obtained using parametric regression analyzes based on fractional polynomials. Covariate analysis (i.e., adjusting for age, body surface) showed that specifc sex-specifc RIs were necessary. Then, age, body height (BH), body weight (BW), body surface area (BSA), and sex-specifc 1st, 2.5th, 5th, 10th, 25th, 50th, 75th, 90th, 95th, 97.5th and 99th percentiles were obtained. Our results were in agreement with and complimentary to available international databases. Conclusion This study provides RIs for echocardiography-derived haemodynamic, LV (structural and functional) and aortic parameters in children, adolescents and young adults considering data obtained from the largest Argentinean database. In early stages of life an adequate interpretation of echocardiography-derived LV and aortic parameters requires considering age, BH, BW, BSA and/or sex-specifc RIs.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Springer
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
CARDIAC INDEX
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CARDIAC OUTPUT
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LEFT VENTRICULAR DIMENSIONS
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LEFT VENTRICULAR FUNCTION
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PERCENTILES
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PEDIATRICS
dc.subject.classification
Sistemas Cardíaco y Cardiovascular
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Medicina Clínica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Percentile curves for left ventricle structural, functional and haemodynamic parameters obtained in healthy children and adolescents from echocardiography-derived data
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-11-18T21:22:34Z
dc.identifier.eissn
1880-344X
dc.journal.volume
18
dc.journal.number
1
dc.journal.pagination
16-43
dc.journal.pais
Japón
dc.journal.ciudad
Tokyo
dc.description.fil
Fil: Diaz, Alberto Alejandro. Universidad Nacional del Centro de la Provincia de Buenos Aires. Instituto de Investigación en Ciencias de La Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentina
dc.description.fil
Fil: Zócalo, Yanina. Universidad de la República. Facultad de Medicina; Uruguay
dc.description.fil
Fil: Bia, Daniel. Universidad de la República. Facultad de Medicina; Uruguay
dc.journal.title
Journal of Echocardiography
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007/s12574-019-00425-0
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s12574-019-00425-0
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