Mostrar el registro sencillo del ítem
dc.contributor.author
Barcelo Martinez, Ernesto
dc.contributor.author
Gelves Ospina, Melissa
dc.contributor.author
Navarro Lechuga, Edgar
dc.contributor.author
Allegri, Ricardo Francisco
dc.contributor.author
Orozco Acosta, Erick
dc.contributor.author
Benitez Agudelo, Juan
dc.contributor.author
Leon Jacobus, Alexandra
dc.contributor.author
Roman, Nestor Fabian
dc.date.available
2020-11-05T14:20:51Z
dc.date.issued
2018-02
dc.identifier.citation
Barcelo Martinez, Ernesto; Gelves Ospina, Melissa; Navarro Lechuga, Edgar; Allegri, Ricardo Francisco; Orozco Acosta, Erick; et al.; Serum cortisol levels and neuropsychological impairments in patients diagnosed with Fibromyalgia; Grupo Ars Xxi Comunicacion S L; Actas Españolas de Psiquiatría; 46; 1; 2-2018; 1-11
dc.identifier.issn
1139-9287
dc.identifier.uri
http://hdl.handle.net/11336/117672
dc.description.abstract
Objective. To describe the relationship between neuropsychological variables and serum cortisol levels as a measure of physiological stress in patients with fibromyalgia.Methodology. A sample of 60 women was intentionally selected: 30 with Fibromyalgia diagnosis and 30 with normal controls. Cortisol levels were determined using two blood samples (AM and PM) and a neuropsychological and emotional battery was applied with a standardized protocol in Colombian population to evaluate different cognitive domains. Comparative and correlational non-parametric analyzes were performed, a multiple regression analysis to determine influences between variables.Results. Significant differences between the study groups in the neuropsychological variables (attention, memory, language, visual-constructive praxis and executive functions (EF), (p<0.05) were found, obtaining better scores in the control group. Significant correlations between the cortisol profile, with false acknowledgments of Rey auditory-verbal learning test, and with perseverative errors of the Wisconsin test were found. Multiple regression analysis predicts the influence of memory and EF variables on the cortisol profile in an 88.7%.Conclusions. The findings show that, in patients with FM, there are neuropsychological alterations, mainly in executive functioning (cognitive flexibility) and episodic memory (evocation and storage). Likewise, executive dysfunction is related to physiological stress reciprocally and in turn areconditioned by emotional alterations such as symptoms of depression, which supports the neurophysiological model that compromises the hypothalamic-pituitary-adrenal axis and the prefrontal cortex, rich in corticosteroid receptors.
dc.format
application/pdf
dc.language.iso
spa
dc.publisher
Grupo Ars Xxi Comunicacion S L
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Pain
dc.subject
Cortisol
dc.subject
Fibromyalgia
dc.subject
Cognition
dc.subject.classification
Neurología Clínica
dc.subject.classification
Medicina Clínica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Serum cortisol levels and neuropsychological impairments in patients diagnosed with Fibromyalgia
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-11-02T17:07:01Z
dc.journal.volume
46
dc.journal.number
1
dc.journal.pagination
1-11
dc.journal.pais
España
dc.journal.ciudad
Madrid
dc.description.fil
Fil: Barcelo Martinez, Ernesto. Universidad de la Costa.; Colombia
dc.description.fil
Fil: Gelves Ospina, Melissa. Universidad de la Costa.; Colombia
dc.description.fil
Fil: Navarro Lechuga, Edgar. Universidad del Norte; Colombia
dc.description.fil
Fil: Allegri, Ricardo Francisco. Universidad de la Costa.; Colombia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Orozco Acosta, Erick. Universidad Simón Bolívar ; Colombia
dc.description.fil
Fil: Benitez Agudelo, Juan. Instituto Colombiano de Neuropedagogía; Colombia
dc.description.fil
Fil: Leon Jacobus, Alexandra. Universidad de la Costa.; Colombia
dc.description.fil
Fil: Roman, Nestor Fabian. Universidad de la Costa.; Colombia
dc.journal.title
Actas Españolas de Psiquiatría
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://pubmed.ncbi.nlm.nih.gov/29417976/
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.actaspsiquiatria.es/repositorio/20/111/ENG/20-111-ENG-1-11-302397.pdf
Archivos asociados