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dc.contributor.author
Biagetti, Marcelo
dc.contributor.author
Arini, Pedro David
dc.contributor.author
Valverde, Esteban Raul
dc.contributor.author
Bertran, Guillermo Claudio
dc.contributor.author
Quinteiro, Ricardo Alberto
dc.date.available
2020-07-20T15:32:18Z
dc.date.issued
2004-03
dc.identifier.citation
Biagetti, Marcelo; Arini, Pedro David; Valverde, Esteban Raul; Bertran, Guillermo Claudio; Quinteiro, Ricardo Alberto; Role of Dipolar and Nondipolar Components of the T Wave in Determining the T Wave Residuum in an Isolated Rabbit Heart Model; Wiley Blackwell Publishing, Inc; Journal Of Cardiovascular Electrophysiology.; 15; 3; 3-2004; 356-363
dc.identifier.issn
1045-3873
dc.identifier.uri
http://hdl.handle.net/11336/109655
dc.description.abstract
Introduction: Repolarization heterogeneity has been shown to constitute a substrate for malignant ventricular arrhythmias. Noninvasive measurement of abnormal repolarization through assessment of QT interval dispersion from the resting standard 12-lead ECG initially had shown promise in assessing arrhythmia risk but was challenged recently. The relative T wave residuum (TWR) has been proposed recently to reflect regional repolarization dispersion more accurately. We analyzed the role played by the dipolar and nondipolar components in determining TWR.
Methods and Results: Singular value decomposition was applied to the repolarization signals obtained from isolated rabbit hearts using a 5 × 8 array multielectrode recording system during premature beats (N = 11) and after d-sotalol (N = 9) exposure. Both the dipolar and nondipolar components of the T wave increased significantly during premature stimulation and after d-sotalol exposure. The relative TWR decreased significantly during premature stimulation but did not change after d-sotalol. Changes in the dipolar and nondipolar components of the second half of the T wave were significantly greater than those corresponding to the first half during premature stimulation, and a significant correlation was observed between the nondipolar components of the second half of the T wave and the Tpeak?end interval. Conclusion: Conditions exist during which both the dipolar and nondipolar components can change simultaneously. Under these conditions, the relative TWR may not reflect regional heterogeneity of repolarization with accuracy. The nondipolar components of the second half of the T wave can be linked to assessment of the transmural dispersion of repolarization.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley Blackwell Publishing, Inc
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
T WAVE RESIDUUM
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ELECTROCARDIOGRAPHIC REPOLARIZATION SIGNAL ANALYSIS
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TRANSMURAL REPOLARIZATION DISPERSION
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SOTALOL
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PREMATURE VENTRICULAR STIMULATION
dc.subject.classification
Otras Ingeniería Eléctrica, Ingeniería Electrónica e Ingeniería de la Información
dc.subject.classification
Ingeniería Eléctrica, Ingeniería Electrónica e Ingeniería de la Información
dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
dc.title
Role of Dipolar and Nondipolar Components of the T Wave in Determining the T Wave Residuum in an Isolated Rabbit Heart Model
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-07-01T17:31:53Z
dc.journal.volume
15
dc.journal.number
3
dc.journal.pagination
356-363
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Biagetti, Marcelo. Universidad Favaloro; Argentina
dc.description.fil
Fil: Arini, Pedro David. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto Argentino de Matemática Alberto Calderón; Argentina. Universidad Favaloro; Argentina
dc.description.fil
Fil: Valverde, Esteban Raul. Universidad Favaloro; Argentina
dc.description.fil
Fil: Bertran, Guillermo Claudio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
dc.description.fil
Fil: Quinteiro, Ricardo Alberto. Universidad Favaloro; Argentina
dc.journal.title
Journal Of Cardiovascular Electrophysiology.
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1540-8167.2004.03466.x
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1046/j.1540-8167.2004.03466.x
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