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dc.contributor.author
Garcia Reiriz, Alejandro Gabriel  
dc.contributor.author
Magallanes, Jorge Federico  
dc.contributor.author
Zupan, Jure  
dc.contributor.author
Líberman, Sara  
dc.date.available
2020-06-23T20:09:16Z  
dc.date.issued
2011-12  
dc.identifier.citation
Garcia Reiriz, Alejandro Gabriel; Magallanes, Jorge Federico; Zupan, Jure; Líberman, Sara; Artificial neural networks to evaluate the boron concentration decreasing profile in Blood-BPA samples of BNCT patients; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 69; 12; 12-2011; 1793-1795  
dc.identifier.issn
0969-8043  
dc.identifier.uri
http://hdl.handle.net/11336/108002  
dc.description.abstract
For the prediction of decay concentration profiles of the p-boronophenylalanine (BPA) in blood during BNCT treatment, a method is suggested based on Kohonen neural networks. The results of a model trained with the concentration profiles from the literature are described. The prediction of the model was validated by the leave-one-out method. Its robustness shows that it is mostly independent on small variations. The ability to fit retrospective experimental data shows an uncertainty lower than the two compartment model used previously.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Pergamon-Elsevier Science Ltd  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Kohonen neural networks  
dc.subject
BNCT  
dc.subject
Concentration profile prediction  
dc.subject
p-Boronophenylalanie  
dc.subject.classification
Química Analítica  
dc.subject.classification
Ciencias Químicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Artificial neural networks to evaluate the boron concentration decreasing profile in Blood-BPA samples of BNCT patients  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2020-05-05T13:03:52Z  
dc.journal.volume
69  
dc.journal.number
12  
dc.journal.pagination
1793-1795  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Nueva Jersey  
dc.description.fil
Fil: Garcia Reiriz, Alejandro Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina  
dc.description.fil
Fil: Magallanes, Jorge Federico. Comisión Nacional de Energía Atómica; Argentina  
dc.description.fil
Fil: Zupan, Jure. National Institute of Chemistry; Eslovenia  
dc.description.fil
Fil: Líberman, Sara. Comisión Nacional de Energía Atómica; Argentina  
dc.journal.title
Applied Radiation and Isotopes  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0969804311002600  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.apradiso.2011.02.055  

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