Artículo
Application of nutrigenomics in small ruminants: Lactation, growth, and beyond
Fecha de publicación:
09/2017
Editorial:
Elsevier Science
Revista:
Journal of Small Ruminant Research
ISSN:
0921-4488
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Ruminants have a very special niche in the animal kingdom, and are the most important livestock species providing milk, meat, and wool for humans from consumption of highly-fibrous feedstuffs. Cattle, goat and sheep have been widely-used for years as models to study ruminal fermentation and the mechanisms whereby tissues utilize nutrients for milk synthesis, growth, wool accretion, and reproduction. The advent of high-throughput technologies to study an animal's genome, proteome, and metabolome (i.e., “omics” tools) offered ruminant scientists the opportunity to study multiple levels of biological information to better understand the whole animal response to nutrition, environment, physiological state, and their interactions. The omics revolution gave rise to the field of nutrigenomics, i.e. the study of the genome-wide influences of nutrition through alteration in mRNA, protein, and metabolite expression or abundance. This field of research is relatively new in ruminants, and particularly sheep and goats. Dietary compounds affect gene expression directly or indirectly via interactions with transcription factors including ligand-dependent nuclear receptors. New knowledge generated through the application of functional analyses of transcriptomic, proteomic, and metabolomic data sets in goat and sheep is discussed.
Palabras clave:
Bioinformatics
,
Genomics
,
Lactation
,
Nutrition
,
Ruminant
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(INPA)
Articulos de UNIDAD EJECUTORA DE INVESTIGACIONES EN PRODUCCION ANIMAL
Articulos de UNIDAD EJECUTORA DE INVESTIGACIONES EN PRODUCCION ANIMAL
Citación
Osorio, Johan S.; Vailati Riboni, Mario; Palladino, Rafael Alejandro; Luo, Jun; Loor, Juan J.; Application of nutrigenomics in small ruminants: Lactation, growth, and beyond; Elsevier Science; Journal of Small Ruminant Research; 154; 9-2017; 29-44
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