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dc.contributor.author
Ruiz, María Sol  
dc.contributor.author
Medina, M.  
dc.contributor.author
Tapia, I.  
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Mordoh, Jose  
dc.contributor.author
Cross, N. C. P.  
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Larripa, Irene Beatriz  
dc.contributor.author
Bianchini, Michele  
dc.date.available
2018-05-13T18:21:52Z  
dc.date.issued
2016-12  
dc.identifier.citation
Ruiz, María Sol; Medina, M.; Tapia, I.; Mordoh, Jose; Cross, N. C. P.; et al.; Standardization of molecular monitoring for chronic myeloid leukemia in Latin America using locally produced secondary cellular calibrators; Nature Publishing Group; Leukemia; 30; 11; 12-2016; 2258-2260  
dc.identifier.issn
0887-6924  
dc.identifier.uri
http://hdl.handle.net/11336/45027  
dc.description.abstract
Residual disease in chronic myeloid leukemia (CML) patients undergoing therapy with tyrosine kinase inhibitors (TKIs) is measured by assessing the quantity of transcripts of the BCR-ABL1 fusion gene in peripheral white blood cells. This analysis is based on reverse-transcription quantitative PCR (RT–qPCR) technology; however, the wide array of methods used worldwide has led to large variation in quantitative BCR-ABL1 measurements, which hamper inter-laboratory comparative studies  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Nature Publishing Group  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Lmc  
dc.subject
Bcr-Abl1  
dc.subject
Fusion Proteins  
dc.subject
Leukemia  
dc.subject.classification
Bioquímica y Biología Molecular  
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Medicina Básica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
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Patología  
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Medicina Básica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Standardization of molecular monitoring for chronic myeloid leukemia in Latin America using locally produced secondary cellular calibrators  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-04-16T14:29:34Z  
dc.journal.volume
30  
dc.journal.number
11  
dc.journal.pagination
2258-2260  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Ruiz, María Sol. Fundación Cáncer. Centro de Investigaciones Oncológicas; Argentina  
dc.description.fil
Fil: Medina, M.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina  
dc.description.fil
Fil: Tapia, I.. Fundación Cáncer. Centro de Investigaciones Oncológicas; Argentina  
dc.description.fil
Fil: Mordoh, Jose. Fundación Cáncer. Centro de Investigaciones Oncológicas; Argentina  
dc.description.fil
Fil: Cross, N. C. P.. Universidad de Southampton Uk; Reino Unido  
dc.description.fil
Fil: Larripa, Irene Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina  
dc.description.fil
Fil: Bianchini, Michele. Fundación Cáncer. Centro de Investigaciones Oncológicas; Argentina  
dc.journal.title
Leukemia  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/leu2016197  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1038/leu.2016.197  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/pmid/27451977