Artículo
Autophagy in development, cell differentiation, and homeodynamics: From molecular mechanisms to diseases and pathophysiology
Fecha de publicación:
01/2014
Editorial:
Hindawi Publishing Corporation
Revista:
BioMed Research International
ISSN:
2314-6141
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The focus of this special issue is to highlight the role of autophagy in cellular homeodynamics, cell differentiation, and development with an outlook to diseases. Autophagy is an evolutionarily conserved catabolic process where cytoplasmic components are sequestered into double-membrane vesicles called autophagosomes, which then fuse with lysosomes and their content is degraded. Despite the significant progress observed over recent years in our understanding of the molecular mechanisms of autophagy, the elucidation of its role in developmental processes still remains a challenge for the scientific community. Given the role of autophagy in pathophysiology and diseases, it is essential to uncover how the mechanisms of autophagy function during developmental processes in the context of tissue and organismal physiology. This special issue contains a collection of four original research papers, four review articles, and one methodology report, covering a broad range of topics.
Palabras clave:
Autophagy
,
Develpmoent
,
Cell Differentiation
,
Pathophysiology
Archivos asociados
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Identificadores
Colecciones
Articulos(IBIMOL)
Articulos de INSTITUTO DE BIOQUIMICA Y MEDICINA MOLECULAR
Articulos de INSTITUTO DE BIOQUIMICA Y MEDICINA MOLECULAR
Citación
Nezis, Ioannis P.; Vaccaro, Maria Ines; Devenish, Rodney J.; Juhász, Gábor; Autophagy in development, cell differentiation, and homeodynamics: From molecular mechanisms to diseases and pathophysiology; Hindawi Publishing Corporation; BioMed Research International; 2014; 1-2014
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