Artículo
Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells
Fecha de publicación:
12/08/2014
Editorial:
American Association for Science and Technology
Revista:
AASCIT communications
ISSN:
2375-3803
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The studies on membrane dynamics in urinary bladder umbrella cells were focused on proteins as important factors for maintaining the permeability barrier and their role as pathways modulators for the discoidal/fusiform endocytic vesicles which is one of the main features of the umbrella cells. However, our workgroup has dedicated to the study of lipid membrane composition and its biological impact in the urothelium. We first studied the lipid membrane composition of rat urothelium modified my dietary treatments differentiated in their fatty acid composition. Changes of lipid composition were related to the asymmetric unit membrane organization and permeability. Finally, we observed that the lipid composition was critically related to the intracellular pathways of discoidal/fusiform endocytic vesicles and their content. The purpose of this communication is to summarize the importance of lipids in the membrane organization and permeability of the apical plasma membrane and endocytic vesicles of umbrella cells.
Palabras clave:
Urothelium
,
Umbrella Cells
,
Plasma Membrane
,
Fatty Acids
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CIQUIBIC)
Articulos de CENTRO DE INVEST.EN QCA.BIOL.DE CORDOBA (P)
Articulos de CENTRO DE INVEST.EN QCA.BIOL.DE CORDOBA (P)
Citación
Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells; American Association for Science and Technology; AASCIT communications; 1; 2; 12-8-2014; 44-47
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