Artículo
Genetic environment of the lnu(B) gene in a Streptococcus agalactiae clinical isolate
Montilla, A.; Zavala, A.; Cáceres Cáceres, R.; Cittadini, R.; Vay, C.; Gutkind, Gabriel Osvaldo
; Famiglietti, Angela María Rosa; Bonofiglio, Laura
; Mollerach, Marta Eugenia
Fecha de publicación:
06/2014
Editorial:
American Society for Microbiology
Revista:
Antimicrobial Agents and Chemotherapy
ISSN:
0066-4804
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
A novel lnu(B)-carrying element of ~12 kb was identified in Streptococcus agalactiae strain isolated from a vaginal swab. The genetic environment in which lnu(B) is located showed similarity to different elements identified in lincosamide resistant Staphylococcous aureus and Enterococcus faecalis. The new element harbored the IS1216 and a transposase gene of the ISL3 family. This is the first report of lnu(B) platform architecture in S. agalactiae. Awareness of the emergence of this mechanism is required as clindamycin resistance may be misidentified in strains with the L phenotype if only erythromycin is tested. The spread to other GBS strains and also to other streptococcal or staphylococcal species should be regarded as a major cause of concern, as ?homing? in intestinal bacteria has been demonstrated to be a way for providing resistance determinants finally incorporated to the pathogenic bacteria.
Palabras clave:
Streptococcus Agalactiae
,
Lnub
,
Antibiotic Resistance
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Articulos(OCA HOUSSAY)
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Citación
Montilla, A.; Zavala, A.; Cáceres Cáceres, R.; Cittadini, R.; Vay, C.; et al.; Genetic environment of the lnu(B) gene in a Streptococcus agalactiae clinical isolate; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 58; 9; 6-2014; 5636-5637
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