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dc.contributor.author
Cuggino, Julio César  
dc.contributor.author
Alvarez Igarzabal, Cecilia Ines  
dc.contributor.author
Strumia, Miriam Cristina  
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Welker, Pia  
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Licha, Kai  
dc.contributor.author
Steinhilber, Dirk  
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Mutihac, Radu Cristian  
dc.contributor.author
Calderón, Marcelo  
dc.date.available
2017-02-13T21:08:44Z  
dc.date.issued
2011-10  
dc.identifier.citation
Cuggino, Julio César; Alvarez Igarzabal, Cecilia Ines; Strumia, Miriam Cristina; Welker, Pia; Licha, Kai; et al.; Thermosensitive nanogels based in dendritic polyglycerol and NIPAm for biomedical applications; Royal Society Of Chemistry; Soft Matter; 7; 23; 10-2011; 11259-11266  
dc.identifier.issn
1744-683X  
dc.identifier.uri
http://hdl.handle.net/11336/12935  
dc.description.abstract
In this paper we describe a methodology for the synthesis of thermoresponsive polyglycerol-based nanogels through precipitation polymerization. A systematic analysis of the preparative conditions and composition regarding the nanogel size is presented. The thermoresponsive properties of the synthesized nanogels, as well as the cytotoxicity and uptake in three different cell lines were investigated. The thermoresponsive behavior, the enhanced biocompatible profile, and the cell penetrating properties of the nanogels highlight the potential of such constructs for application as smart, environmentally-responsive materials.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Royal Society Of Chemistry  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Thermoresponsive Nanogels  
dc.subject
Nanogels  
dc.subject
Hyperbranched Polyglycerol  
dc.subject.classification
Nano-materiales  
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Nanotecnología  
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INGENIERÍAS Y TECNOLOGÍAS  
dc.title
Thermosensitive nanogels based in dendritic polyglycerol and NIPAm for biomedical applications  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2017-02-09T13:51:54Z  
dc.journal.volume
7  
dc.journal.number
23  
dc.journal.pagination
11259-11266  
dc.journal.pais
Reino Unido  
dc.description.fil
Fil: Cuggino, Julio César. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina  
dc.description.fil
Fil: Alvarez Igarzabal, Cecilia Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina  
dc.description.fil
Fil: Strumia, Miriam Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina  
dc.description.fil
Fil: Welker, Pia. mivenion GmbH; Alemania  
dc.description.fil
Fil: Licha, Kai. mivenion GmbH; Alemania  
dc.description.fil
Fil: Steinhilber, Dirk. Freie Universität Berlin; Alemania  
dc.description.fil
Fil: Mutihac, Radu Cristian. Freie Universität Berlin; Alemania  
dc.description.fil
Fil: Calderón, Marcelo. Freie Universität Berlin; Argentina  
dc.journal.title
Soft Matter  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1039/C1SM06357J  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/Content/ArticleLanding/2011/SM/c1sm06357j#!divAbstract